Novel Natural and Synthetic Anticandidal Therapeutic Peptides to Combat Drug-Resistant Infections
Medical Sciences Forum, 2023 Candida species are considered as common flora of the healthy human mycobiome and occur on skin, mucosal surfaces of gastrointestinal and genitourinary tracks. Pathogenic Candida spp., reported to cause skin, vaginal and oral infections. Extensive use of
Deepika Sharma
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Aspiring Antifungals: Review of Current Antifungal Pipeline Developments
Journal of Fungi, 2020 Invasive fungal infections are associated with significant morbidity and mortality, and their management is restricted to a variety of agents from five established classes of antifungal medication.
Thomas J. Gintjee +2 more
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Antifungal Combinations in Dermatophytes
Journal of Fungi, 2021 Dermatophytes are the most common cause of fungal infections worldwide, affecting millions of people annually. The emergence of resistance among dermatophytes along with the availability of antifungal susceptibility procedures suitable for testing ...
Lucia Brescini +3 more
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Use of volatile fingerprints for rapid screening of antifungal agents for efficacy against dermatophyte Trichophyton species [PDF]
, 2010 The potential of using an electronic nose (E-nose) as a rapid technique for screening the responses of dermatophytes to antifungal agents was studied.
Barr, Hugh +9 more
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Modes of action of the new arylguanidine abafungin beyond interference with ergosterol biosynthesis and in vitro activity against medically important fungi [PDF]
, 2008 Background: In contrast to the increasing numbers of agents for the treatment of invasive fungal infections, discoveries of new antifungal agents with therapeutic value in dermatomycoses are reported only rarely.
Borelli, Claudia +10 more
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Pharmacodynamic Effects of Simulated Standard Doses of Antifungal Drugs against Aspergillus Species in a New In Vitro Pharmacokinetic/Pharmacodynamic Model [PDF]
, 2011 In conventional MIC tests, fungi are exposed to constant drug concentrations, whereas in vivo, fungi are exposed to changing drug concentrations.
Thomas J. Walsh +11 more
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Flucytosine and cryptococcosis: time to urgently address the worldwide accessibility of a 50-year-old antifungal. [PDF]
, 2013 Current, widely accepted guidelines for the management of HIV-associated cryptococcal meningoencephalitis (CM) recommend amphotericin B combined with flucytosine (5-FC) for ≥2 weeks as the initial induction treatment of choice.
A. Loyse +9 more
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Exploring hidden dimensions of soil fungal biodiversity: A simple technique to detect soil fungi resistant to antifungal compounds [PDF]
, 2010 Soils are known to be ultimate and complex reservoirs of microbial diversity. The complex dimensions of bacterial and fungal diversity in tropical soils and microbial community dynamics are underexplored.
Sonashia Velho-Pereira +1 more
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Cyclic imide derivatives: As promising scaffold for the synthesis of antimicrobial agents
Journal of Research in Medical Sciences, 2018 Cyclic imides as building blocks in the synthesis of natural products, drugs and polymers display a diverse of pharmacological activities such as antibacterial, antifungal, anticonvulsant, anticancer, and anti-inflammatory effects. This review summarizes
Farshid Hassanzadeh, Elham Jafari
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, 2004 With the relentless increase in invasive fungal infections, particularly in critically ill and immunocompromised patients, it is good to know that there are new additions to the antifungal armamentarium.
Shetty, Anjali, Barnes Ann, Rosemary
core +4 more sources