Results 91 to 100 of about 3,938,965 (348)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To investigate the overall use of prescription medications among individuals with multiple sclerosis compared to the general population, with a focus on treatments beyond disease‐modifying therapies. Methods We conducted a nationwide, registry‐based study in Denmark.
Josefine Windfeld‐Mathiasen +4 more
wiley +1 more source
Pre-Existing Liver Disease and Toxicity of Antifungals
Journal of Fungi, 2018 Pre-existing liver disease in patients with invasive fungal infections further complicates their management. Altered pharmacokinetics and tolerance issues of antifungal drugs are important concerns.
Nikolaos Spernovasilis +1 more
doaj +1 more source
Scientific Reports, 2019 Candida albicans is the most frequently isolated fungal species in hospital settings worldwide. However, non-albicans Candida species with decreased susceptibility to antifungals have emerged as an important cause of fungemia. The aims of this study were
E. Lindberg +3 more
semanticscholar +1 more source
Original Multivalent Gold (III) and Dual Gold(III)-Copper(II) Conjugated Phosphorus Dendrimers as Potent Antitumoral and Antimicrobial Agents [PDF]
, 2017 Original metallophosphorus dendrimers (generation 3, 48 terminal groups) have been prepared via the complexation of phosphorus dendrimers bearing imino-pyridino end groups with Au(III) or with both Au(III) and Cu(II).
Serge M. Mignani +11 more
core +2 more sources
Advanced Functional Materials, EarlyView.Biopolymers are sustainable, biodegradable alternatives to petroleum‐based plastics for food packaging. Its adoption is often limited by poor mechanical strength, barrier properties, and improved thermal stability through the incorporation of nanofillers.
Himakshi Baishya +2 more
wiley +1 more source
Combination of Posaconazole and Amphotericin B in the Treatment of Candida glabrata Biofilms
Microorganisms, 2018 Candidemia cases have been increasing, especially among immunosuppressed patients. Candida glabrata is one of the most resistant Candida species, especially to the azole drugs, resulting in a high demand for therapeutic alternatives.
Célia F. Rodrigues +2 more
doaj +1 more source
Antimicrobial Agents and Chemotherapy, 2018 F901318 (olorofim) is a novel antifungal drug that is highly active against Aspergillus species. Belonging to a new class of antifungals called the orotomides, F901318 targets dihydroorotate dehydrogenase (DHODH) in the de novo pyrimidine biosynthesis ...
Saskia du Pré +8 more
semanticscholar +1 more source
A marine microbiome antifungal targets urgent-threat drug-resistant fungi
Science, 2020 Prospecting for antifungal molecules Marine bacteria produce a plethora of natural products that often have unusual chemical structures and corresponding reactivity, which sometimes translate into a valuable biological function. Zhang et al.
Fan Zhang +21 more
semanticscholar +1 more source
Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks
Advanced Functional Materials, EarlyView.This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson +12 more
wiley +1 more source
Frontiers in Pharmacology, 2020 Precision dosing for many antifungal drugs is now recommended. Saliva sampling is considered as a non-invasive alternative to plasma sampling for therapeutic drug monitoring (TDM).
Hannah Yejin Kim +11 more
doaj +1 more source