Results 111 to 120 of about 3,938,965 (348)

Synergistic antifungal effects and mechanisms of amantadine hydrochloride combined with azole antifungal drugs on drug-resistant Candida albicans

Frontiers in Cellular and Infection Microbiology
IntroductionThe increasing resistance of Candida albicans (C. albicans) to conventional antifungal drugs poses a great challenge to the clinical treatment of infections caused by this yeast.
Xiuyun Li, Yuanyuan Zhi, Ximeng Duan, Xu Chen, Min Cui, Shicun Zheng   +5 more
doaj   +1 more source

Increasing Candida antifungal resistance in Eastern India (2019-2023): A notable rise in amphotericin B resistance [PDF]

Current Medical Mycology
Background and Purpose: This study analyzed the species diversity and antifungal drug sensitivity of Candida isolates reported from 2019 to 2023 at our hospital to guide empirical treatment protocols.Materials and Methods: Clinical samples were cultured ...
Poulami Mukherjee, Purushottam Dutta, Apoorbaa Roy, Prabuddha Mukhopadhyay   +3 more
doaj   +1 more source

Anti-Candida targets and cytotoxicity of casuarinin isolated from Plinia cauliflora leaves in a bioactivity-guided study [PDF]

, 2013
Peer reviewedPublisher ...
Gow, Neil A R, Lee, Keunsook, Munro, Carol A, Pietro, Rosemeire C L R, Preechasuth, Kanya, Santos, Emerson, Severi, Juliana A, Souza-Moreira, Tatiana M, Vilegas, Wagner   +8 more
core   +4 more sources

Introduction to Antifungal Drugs [PDF]

Clinical Infectious Diseases, 2000
In the United States, only 10 antifungal drugs are currently approved by the Food and Drug Administration (FDA) for the therapy of systemic fungal infections. As shown in table 1, these drugs belong to 3 principal classes: polyenes, pyrimidines, and azoles.
openaire   +3 more sources

Electrosynthesis of Bioactive Chemicals, From Ions to Pharmaceuticals

Advanced Functional Materials, EarlyView.
This review discusses recent advances in electrosynthesis for biomedical and pharmaceutical applications. It covers key electrochemical materials enabling precise delivery of ions and small molecules for cellular modulation and disease treatment, alongside catalytic systems for pharmaceutical synthesis.
Gwangbin Lee, Sojin Kim, Myeongeun Lee, Kyoungsuk Jin, Jimin Park   +4 more
wiley   +1 more source

The Viscoelastic Properties of the Fungal Cell Wall Allow Traffic of AmBisome as Intact Liposome Vesicles

mBio, 2018
The fungal cell wall is a critically important structure that represents a permeability barrier and protective shield. We probed Candida albicans and Cryptococcus neoformans with liposomes containing amphotericin B (AmBisome), with or without 15-nm ...
Louise Walker, Prashant Sood, Megan D. Lenardon, Gillian Milne, Jon Olson, Gerard Jensen, Julie Wolf, Arturo Casadevall, Jill Adler-Moore, Neil A. R. Gow   +9 more
doaj   +1 more source

Rad53- and Chk1-Dependent DNA Damage Response Pathways Cooperatively Promote Fungal Pathogenesis and Modulate Antifungal Drug Susceptibility

mBio, 2019
Genome instability is detrimental for living things because it induces genetic disorder diseases and transfers incorrect genome information to descendants.
Kwang-Woo Jung, Yeonseon Lee, E. Huh, Soo Chan Lee, Sangyong Lim, Yong-Sun Bahn   +5 more
semanticscholar   +1 more source

Green synthesis of highly functionalized octahydropyrrolo[3,4-c]pyrrole derivatives using subcritical water, and their anti(myco)bacterial and antifungal activity [PDF]

, 2018
A series of novel 2-(thiazol-2-yl)-octahydropyrrolo[3,4-c]pyrroles was synthesized by reaction of octahydropyrrolo[3,4-c]pyrrole N-benzoylthiourea derivatives and α-haloketones in subcritical water at 130 °C in 75-91% yield.
De Coen, Laurens, Gemili, Muge, Nural, Yahya, Ulger, Mahmut, Yabalak, Erdal   +4 more
core   +1 more source

Polyferrocene‐Based Cubosomes: Conversion to Magnetic Mesoporous Microparticles, Supramolecular Modification, and Oxidation Response

Advanced Functional Materials, EarlyView.
Polyferrocene block copolymers are synthesized and assembled into micron‐sized polymer cubosomes with double diamond lattice and pore diameter of ≈30 nm. The ferrocene functionality is retained within the polymer cubosome wall as demonstrated on supramolecular modification, and oxidative disassembly.
Chin Ken Wong, Suna Azhdari, Marvin Foith, Chen Chen, André H. Gröschel   +4 more
wiley   +1 more source

Fonsecaea pedrosoi Sclerotic Cells: Secretion of Aspartic-Type Peptidase and Susceptibility to Peptidase Inhibitors

Frontiers in Microbiology, 2018
Fonsecaea pedrosoi is a dematiaceous fungus and the main causative agent of chromoblastomycosis that is a chronic disease usually affecting the human skin and subcutaneous tissues, which causes deformations and incapacities, being frequently refractory ...
Vanila F. Palmeira, Vanila F. Palmeira, Fatima R. V. Goulart, Marcela Q. Granato, Daniela S. Alviano, Celuta S. Alviano, Lucimar F. Kneipp, André L. S. Santos, André L. S. Santos   +8 more
doaj   +1 more source