Results 121 to 130 of about 3,938,965 (348)
Fabrication of a drug delivery system that enhances antifungal drug corneal penetration
Drug Delivery, 2018 Fungal keratitis (FK) remains a severe eye disease, and effective therapies are limited by drug shortages and critical ocular barriers. Despite the high antifungal potency and broad spectrum of econazole, its strong irritant and insolubility in water ...
Jingguo Li +6 more
semanticscholar +1 more source
Rapid Deep Vat Printing Using Photoclickable Collagen‐Based Bioresins
Advanced Healthcare Materials, EarlyView.Collagen‐based resin formulations based on thiol‐ene photoclick chemistry are demonstrated. These resins enable easy handleability under neutral conditions and further allow facile fabrication of multicellular tissue constructs via tomographic or FLight printing.
Michael Winkelbauer +8 more
wiley +1 more source
Acta Crystallographica Section E, 2014 The asymmetric unit of the title salt, C4H5FN3O+·C6H4NO3−, contains one 4-amino-5-fluoro-2-oxo-2,3-dihydropyrimidin-1-ium (5-fluorocytosinium, 5FC) cation and a 3-hydroxypicolinate (3HAP) anion.
Ammasai Karthikeyan +2 more
doaj +1 more source
Screening of the central nervous system in children with invasive pulmonary aspergillosis [PDF]
, 2014 Peer reviewedPublisher ...
Broenen, Emmi +5 more
core +2 more sources
Advanced Healthcare Materials, EarlyView.This study develops a 3D vascular injury model using a microphysiological system that mimics key features of intimal hyperplasia. Antiproliferative drugs reduced VSMC proliferation but worsened endothelialdenudation. A combination of diphenyleneiodonium and quercetin effectively reduced proliferation and migration of VSMC and inflammation while ...
Ungsig Nam +7 more
wiley +1 more source
Synthesis of Simplified Azasordarin Analogs as Potential Antifungal Agents [PDF]
, 2019 A new series of simplified azasordarin analogs was synthesized using as key steps a Diels–Alder reaction to generate a highly substituted bicyclo[2.2.1]heptane core, followed by a subsequent nitrile alkylation.
Dockendorff, Chris, Wu, Yibiao
core +4 more sources
Advanced Healthcare Materials, EarlyView.The foreign body response (FBR) to biomaterials is primarily driven by macrophages, which often fuse into destructive foreign body giant cells (FBGCs). To address the limited understanding of FBGC formation, a novel microscale core–shell hydrogel 3D model is developed using heterogeneous alginate‐collagen microcapsules with varying stiffness, offering ...
Manisha Mahanty +5 more
wiley +1 more source
Frontiers in Analytical ScienceIntroductionItraconazole is a widely used broad-spectrum antifungal drug on a global scale. However, its poor water solubility necessitates the development of advanced formulations for its effective use.
Patricia G. Ferreira +5 more
doaj +1 more source
HIV & AIDS Review. International Journal of HIV-Related Problems, 2020 Oropharyngeal candidiasis (OPC) is considered the most common fungal infection in human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) patients. Antifungal drug, azole group, is the preferred treatment.
Satutya Wicaksono +4 more
doaj +1 more source
Unveiling interactions between DNA and cytotoxic 2-arylpiperidinyl-1,4-naphthoquinone derivatives: A combined electrochemical and computational study [PDF]
, 2018 Indexación: Scopus.Three 2-arylpiperidinyl-1,4-naphthoquinone derivatives were synthesized and evaluated in vitro to determine their cytotoxicity on cancer and normal cell lines.
Canales, C. +4 more
core +1 more source