Results 261 to 270 of about 3,938,965 (348)

Toxic Evaluations of Calea phyllolepis Extracts Standardized on 6‐epi‐β‐Verbesinol Coumarate and Its In Silico Prediction of the Toxicity

Chemistry &Biodiversity, EarlyView.
In vivo and in silico toxicological effects of Calea phyllolepis extracts Standardized on 6‐epi‐β‐Verbesinol Coumarate. ABSTRACT Medicinal plants are traditionally used in folk medicine. Still, there is a misconception about the safety/efficacy of natural treatments, which results in few studies on the toxic, genotoxic, and mutagenic potential of ...
Suele Bierhals Vencato, Guilherme Borsoi, Cleverson Feistel, Mariele Feiffer Charão, Angélica Rocha Joaquim, Jaqueline Nascimento Picada, Alexandre de Barros Falcão Ferraz   +6 more
wiley   +1 more source

Clinical Significance of Azole Antifungal Drug Cross-Resistance in Candida glabrata

, 2006
Anil A. Panackal, Jennifer L. Gribskov, Janet F. Staab, Katharine A. Kirby, Michael G. Rinaldi, Kieren A. Marr   +5 more
openalex   +1 more source

Carum carvi and Ormenis multicaulis Extracts: Chemical Analysis and In Vivo Experiments to Evaluate the Synergistic Analgesic and Anti‐Inflammatory Effects

Chemistry &Biodiversity, EarlyView.
ABSTRACT The purpose of the present investigation was to determine the effects of combination of Ormenis multicaulis dry flower methanolic extracts and Carum carvi seed methanolic extracts on pain and inflammation, compared to their use separately. High‐performance liquid chromatography (HPLC) analysis of methanolic extracts showed the presence of ...
El Mahdi Wakrim, Karima Raoui, Hamid Kabdy, Jawad Laadraoui, Mehdi Ait Laaradia, Chafik Terrafe, Sami Mnif, Brahim Bouizgarne, Stefania Garzoli, Abderrahman Chait   +9 more
wiley   +1 more source

ID2 OUTCOMES ASSOCIATED WITH ANTIFUNGAL DRUG SWITCHING IN PATIENTS WITH SERIOUS CANDIDA INFECTIONS

, 2006
Jia‐Qiang He, C Wang, Bruce A. Griffin, Joseph L. Smith, A. Cecile Mahoney, E Burleigh   +5 more
openalex   +1 more source

Plinia cauliflora Leaf Extract Promotes Wound Healing Through Anti‐Inflammatory, Antioxidant, and Antibacterial Actions

Chemistry &Biodiversity, EarlyView.
ABSTRACT Plinia cauliflora (DC.) Kausel (jabuticaba) is traditionally used by Brazilian indigenous communities for therapeutic purposes, including the treatment of wounds and inflammation. This study investigated the phytochemical composition and biological activities of an ethanolic extract derived from P.
Priscila de Lima Paula, Mariana Hauck Vianna, Júlia Bertolini Fajardo, Ana Barbara Polo, Lara Melo Campos, Thayná Gomes Ferreira, Ari Sérgio de Oliveira Lemos, Thalita de Freitas Souza, Lívia Rodrigues Gamarano, Maria Clara Machado Resende Guedes, Samira Aparecida Coelho Souza, Ayrton Senna Pinheiro, Leandro De Santis Ferreira, José Maria Barbosa‐Filho, Elaine Soares Coimbra, Gilson Costa Macedo, Luciana Moreira Chedier, Rodrigo Luiz Fabri   +17 more
wiley   +1 more source

Antifungal drug resistance among Candida species: mechanisms and clinical impact

Mycoses (Berlin), 2015
M. Sanguinetti, B. Posteraro, C. Lass‐Flörl   +2 more
semanticscholar   +1 more source

Exploring the Antiproliferative Activity of Flavolignans From the Leaves of Casearia arborea (Salicaceae)

Chemistry &Biodiversity, EarlyView.
ABSTRACT The Casearia genus (Salicaceae) is well known as a source of natural antitumor prototypes, as described for clerodane diterpenes. In this way, the dichloromethane phase from leaves of Casearia arborea was phytochemically evaluated in liquid chromatography coupled to high‐resolution mass spectrometry, furnishing flavonoid, flavolignan, and ...
Augusto L. Santos, Mariana T. Rodrigues, Ana Paula Michelli, Rodrigo E. Tamura, Ileana G. S. de Rubió, Marisi G. Soares, Marcelo J. P. Ferreira, Patricia Sartorelli   +7 more
wiley   +1 more source

Concentration-Dependent Synergy and Antagonism within a Triple Antifungal Drug Combination againstAspergillusSpecies: Analysis by a New Response Surface Model

, 2007
Joseph Meletiadis, Theodouli Stergiopoulou, Elizabeth O’Shaughnessy, Joanne Peter, Thomas J. Walsh   +4 more
openalex   +1 more source

Evolution of the Sterol Biosynthetic Pathway of Pythium insidiosum and Related Oomycetes Contributes to Antifungal Drug Resistance

Antimicrobial Agents and Chemotherapy, 2017
Tassanee Lerksuthirat, A. Sangcakul, Tassanee Lohnoo, Wanta Yingyong, T. Rujirawat, T. Krajaejun   +5 more
semanticscholar   +1 more source

Synthesis, In Silico, and Biological Evaluation of Non‐Hydroxamate Benzoic Acid–Based Derivatives as Potential Histone Deacetylase Inhibitors (HDACi)

Chemistry &Biodiversity, EarlyView.
Compound A3bn exhibited strong binding affinities for HDAC2, HDAC6, and HDAC8. A3bn’s anticancer IC50 values were similar to those of SAHA. Cell death resulted from the extrinsic apoptotic pathway. Compound A3bn, a hydrophilic linker, which promotes zinc coordination, may be the cause of its increased activity across HDAC isoforms. ABSTRACT Unregulated
Nedaa A. Abd Al Rahim, Ammar A. Razzak Mahmood, Lubna H. Tahtamouni, Randa M. Bawadi, Ayah Y. Almasri, Marya A. Hamad, Nour A. Hussein, Salem R. Yasin, Abdulrahman M. Saleh   +8 more
wiley   +1 more source