Analysis of imidazoles and triazoles in biological samples after MicroExtraction by packed sorbent [PDF]
, 2017 This paper reports the MEPS-HPLC-DAD method for the simultaneous determination of 12 azole drugs (bifonazole, butoconazole, clotrimazole, econazole, itraconazole, ketoconazole, miconazole, posaconazole, ravuconazole, terconazole, tioconazole and ...
Campestre, Cristina +9 more
core +1 more source
Exploring the Molecular Basis of Antifungal Synergies Using Genome-Wide Approaches
Frontiers in Microbiology, 2012 Drug resistance poses a significant challenge in antifungal therapy since resistance has been found for all known classes of antifungal drugs. The discovery of compounds that can act synergistically with antifungal drugs is an important strategy to ...
Ameeta eAgarwal +6 more
doaj +1 more source
In Vitro and In Vivo Assessment of FK506 Analogs as Novel Antifungal Drug Candidates
Antimicrobial Agents and Chemotherapy, 2018 FK506 (tacrolimus) is an FDA-approved immunosuppressant indicated for the prevention of allograft rejections in patients undergoing organ transplants.
Yeonseon Lee +13 more
semanticscholar +1 more source
Pharmacodynamics of the Orotomides against Aspergillus fumigatus: New Opportunities for Treatment of Multidrug-Resistant Fungal Disease. [PDF]
, 2017 F901318 is an antifungal agent with a novel mechanism of action and potent activity against Aspergillus spp. An understanding of the pharmacodynamics (PD) of F901318 is required for selection of effective regimens for study in phase II and III clinical ...
Adam Johnson +12 more
core +2 more sources
APX001 Is Effective in the Treatment of Murine Invasive Pulmonary Aspergillosis. [PDF]
, 2019 Invasive pulmonary aspergillosis (IPA) due to Aspergillus fumigatus is a serious fungal infection in the immunosuppressed patient population. Despite the introduction of new antifungal agents, mortality rates remain high, and new treatments are needed ...
Alkhazraji, Sondus +7 more
core
Adhesive Properties and Sensitivity to Antifungal Drugs of Candida Albicans, Which Are Released From Patients of Gastroenterological Profile with Candidiasis of the Mucosa of the Upper Part of the Digestive Tract [PDF]
, 2016 Candida albicans were released from 146 loci from 89 patients in order to perform the investigation. The fourth stage of contamination by Candida albicans in the scrape from the tongue and candidiasis of the esophagus or /and the stomach during ...
Kushnirenko, I. (Inessa)
core +2 more sources
Targeting Candida albicans filamentation for antifungal drug development
Virulence, 2017 Candida albicans remains the main etiological agent of candidiasis, as this otherwise normal commensal of humans is capable of causing active infection in immune- and medically-compromised patients.
T. Vila +5 more
semanticscholar +1 more source
Calli Essential Oils Synergize with Lawsone against Multidrug Resistant Pathogens. [PDF]
, 2017 The fast development of multi-drug resistant (MDR) organisms increasingly threatens global health and well-being. Plant natural products have been known for centuries as alternative medicines that can possess pharmacological characteristics, including ...
Alsaadi, Abrar I +6 more
core +2 more sources
Indian Dermatology Online Journal, 2019 © 2019 Indian Dermatology Online Journal | Published by Wolters Kluwer Medknow Dermatophytes are the most commonly encountered fungi in humans and other vertebrates that spread through direct contact with infected humans, animals, and soil.[1] Infections
S. Dogra, Dipika Shaw, S. Rudramurthy
semanticscholar +1 more source
Allergic bronchopulmonary aspergillosis: diagnostic and treatment challenges [PDF]
, 2016 Allergic bronchopulmonary aspergillosis (ABPA) is a pulmonary disorder, occurring mostly in asthmatic and cystic fibrosis patients, caused by an abnormal T-helper 2 lymphocyte response of the host to Aspergillus fumigatus antigens.
CINICOLA, BIANCA LAURA +3 more
core +1 more source