Results 181 to 190 of about 4,137,509 (275)

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Boronic Acid Inhibitors of β‐Lactamases: A Promising Strategy Against Antimicrobial Resistance

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT The rise of antimicrobial resistance (AMR) poses a critical threat to global health, mostly due to the proliferation of β‐lactamases, a class of enzymes responsible for the inactivation of β‐lactam antibiotics. Among the most promising strategies to restore β‐lactam efficacy is the use of β‐lactamase inhibitors (BLIs), with boronic acid ...
Nicolò Santi   +4 more
wiley   +1 more source

Analysis of Antifungal Drug Resistance Among <i>Candida</i> Spp. and Other Pathogenic Yeasts Isolated from Patients in Eastern Poland: Diagnostic Problems. [PDF]

open access: yesInfect Drug Resist
Olender A   +9 more
europepmc   +1 more source

Artificial Intelligence‐Driven Natural Product Drug Discovery: From Computational Genome Mining to Clinical Translation

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Natural products (NPs) have historically yielded numerous therapeutic agents, yet their integration into modern drug discovery has been constrained by chemical complexity, low abundance, laborious dereplication, and limited target annotation.
Antonio Lavecchia
wiley   +1 more source

Cross‐Platform Concordance Between Metagenomic and Targeted DNA Sequencing for Diagnosing Polymicrobial Infections in an Immunosuppressed Patient: A Case Report

open access: yesMedicine Advances, EarlyView.
An immunosuppressed 40‐year‐old man developed rapidly progressive polymicrobial pneumonia caused by Pneumocystis jirovecii and carbapenem‐resistant Klebsiella pneumoniae. Three metagenomic next‐generation sequencing (mNGS) and targeted next‐generation sequencing (tNGS) workflows with different assay designs and technical parameters consistently ...
Mengxia Wang, Jielun Wen, Liyue Sun
wiley   +1 more source

Applications of nanocarrier‐delivered RNA interference in agricultural biological control (2009–2025)

open access: yesNew Plant Protection, EarlyView.
Despite 17 years of development, the effectiveness of nanocarrier‐delivered RNAi pesticide (NDRP) for agricultural biological control remains limited. The successful development of effective NDRP development requires the coordinated optimization of target gene selection and nanocarrier properties, including RNA dosage, multi‐gene targeting, protection ...
Shi Dong Wang   +4 more
wiley   +1 more source

Responsible agrivoltaics in temperate Europe: Making systems work for plants, people, and climate

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Conceptual framework illustrating the three conditions for responsible AV in temperate regions: sustained plant productivity across rotations, preservation of soil and hydrological integrity, and social license for landscape integration. Multi‐site European evidence highlights how design choices shape trade‐offs among these dimensions.
Maryam Rahimi Jahangirlou   +13 more
wiley   +1 more source

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