Results 81 to 90 of about 3,996,806 (388)

Original Multivalent Gold (III) and Dual Gold(III)-Copper(II) Conjugated Phosphorus Dendrimers as Potent Antitumoral and Antimicrobial Agents [PDF]

open access: yes, 2017
Original metallophosphorus dendrimers (generation 3, 48 terminal groups) have been prepared via the complexation of phosphorus dendrimers bearing imino-pyridino end groups with Au(III) or with both Au(III) and Cu(II).
Serge M. Mignani   +11 more
core   +2 more sources

Current Insights on Antifungal Therapy: Novel Nanotechnology Approaches for Drug Delivery Systems and New Drugs from Natural Sources

open access: yesPharmaceuticals, 2020
The high incidence of fungal infections has become a worrisome public health issue, having been aggravated by an increase in host predisposition factors.
Filipa Sousa   +3 more
semanticscholar   +1 more source

Selective Laser Sintering 3D Printing of Drug‐Loaded Intravitreal Implants

open access: yesAdvanced Functional Materials, EarlyView.
Selective laser sintering enables the fabrication of biodegradable and biocompatible intravitreal implants with tunable microstructures for sustained drug delivery. By modulating laser scanning speed, the polymer matrix architecture is engineered to control the release kinetics of dexamethasone and riboflavin over several months. This approach offers a
Iria Seoane‐Viaño   +5 more
wiley   +1 more source

Pre-Existing Liver Disease and Toxicity of Antifungals

open access: yesJournal of Fungi, 2018
Pre-existing liver disease in patients with invasive fungal infections further complicates their management. Altered pharmacokinetics and tolerance issues of antifungal drugs are important concerns.
Nikolaos Spernovasilis   +1 more
doaj   +1 more source

Activity and Mechanism of Action of Antifungal Peptides from Microorganisms: A Review

open access: yesMolecules, 2021
Harmful fungi in nature not only cause diseases in plants, but also fungal infection and poisoning when people and animals eat food derived from crops contaminated with them.
Tianxi Li   +6 more
doaj   +1 more source

Topical Application of Imiquimod as a Treatment for Chromoblastomycosis [PDF]

open access: yes, 2014
Peer reviewedPublisher ...
Belda Junior, Walter   +7 more
core   +1 more source

Antifungal Drugs: Special Problems Treating Central Nervous System Infections

open access: yesJournal of Fungi, 2019
Treating fungal infections in the central nervous system (CNS) remains a challenge despite the availability of new antifungal agents. Therapy is limited by poor understanding of the kinetic properties of antifungal drugs in the CNS compounded by lack of ...
E. Ashley
semanticscholar   +1 more source

Antifungal Application of Nonantifungal Drugs [PDF]

open access: yesAntimicrobial Agents and Chemotherapy, 2014
ABSTRACTCandidaspecies are the cause of 60% of all mycoses in immunosuppressed individuals, leading to ∼150,000 deaths annually due to systemic infections, whereas the current antifungal therapies either have toxic side effects or are insufficiently efficient.
Stylianou, Marios   +5 more
openaire   +3 more sources

Nanoparticles Decorated Nanotubes: Advanced Local Therapies From Anodized Nanoengineered Titanium Implants

open access: yesAdvanced Functional Materials, EarlyView.
This comprehensive review explores therapeutic titanium implants designed to enhance integration and provide superior antibacterial efficacy. It is focused on anodized titanium implants with titania nanotubes (TNTs) loaded with nanoparticles (NPs) for local therapeutic release, enhancing bioactivity and bactericidal functions.
Divya Chopra   +5 more
wiley   +1 more source

Photodynamic therapy combined with antifungal drugs against chromoblastomycosis and the effect of ALA-PDT on Fonsecaea in vitro

open access: yesPLoS Neglected Tropical Diseases, 2019
Background Chromoblastomycosis is a chronic skin and subcutaneous fungal infection caused by dematiaceous fungi and is associated with low cure and high relapse rates.
Yongxuan Hu   +10 more
semanticscholar   +1 more source

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