The evolution of antifungal therapy: Traditional agents, current challenges and future perspectives
Fungal infections kill more than 3 million people every year. This high number reflects the significant challenges that treating these diseases worldwide presents.
Cássia Milena de Souza +3 more
doaj +1 more source
Exploring the Molecular Basis of Antifungal Synergies Using Genome-Wide Approaches
Drug resistance poses a significant challenge in antifungal therapy since resistance has been found for all known classes of antifungal drugs. The discovery of compounds that can act synergistically with antifungal drugs is an important strategy to ...
Ameeta eAgarwal +6 more
doaj +1 more source
AI–Guided 4D Printing of Carnivorous Plants–Inspired Microneedles for Accelerated Wound Healing
This work presents an artificial intelligence (AI)‐guided 4D‐printed microneedle platform inspired by carnivorous plants for wound healing. A thermo‐responsive shape memory polymer enables body temperature–triggered self‐coiling for autonomous wound closure.
Hyun Lee +21 more
wiley +1 more source
Natural Compounds with Antifungal Properties against Candida albicans and Identification of Hinokitiol as a Promising Antifungal Drug [PDF]
Louis Camaioni +6 more
openalex +1 more source
Conductive Hydrogels for Exogenous Sensing and Cell Fate Control
We engineer electrically conductive hydrogels by combining sulfated glycosaminoglycans with semiconducting polymers. These hydrogels bind bioactive proteins, including growth factors, whose release or retention can be modulated by low‐voltage stimulation. The hydrogels are also integrated as 3D channels in organic electrochemical transistors as part of
Teuku Fawzul Akbar +15 more
wiley +1 more source
Antifungal susceptibility profiles of 1698 yeast reference strains revealing potential emerging human pathogens. [PDF]
New molecular identification techniques and the increased number of patients with various immune defects or underlying conditions lead to the emergence and/or the description of novel species of human and animal fungal opportunistic pathogens. Antifungal
Marie Desnos-Ollivier +4 more
doaj +1 more source
An Advanced Molecularly Imprinted Polymer‐Based Electrochemical Aptasensor for Carbendazim Detection
A dual‐recognition electrochemical aptasensor that integrates a molecular imprinted polymer (MIP) and an aptamer is developed for the detection of a common pesticide, carbendazim (CBZ). The resulting sensor exhibits enhanced selectivity toward CBZ over structurally similar compounds and achieves a low detection limit of 1.3 nm, demonstrating its ...
Suthira Pushparajah +3 more
wiley +1 more source
An Accessible Microfluidic Platform for the Generation of Polarized Brain Organoids
This study presents an accessible double‐gradient microfluidic device that enables controlled morphogen delivery and spatially polarized differentiation in brain organoids. By integrating a pump‐free design and stable fabrication method, the platform generates dorsal–ventral neuronal asymmetry, offering a reproducible and versatile approach to model ...
Daniel Pérez‐Calixto +6 more
wiley +1 more source
Habip Gedik Department of Infectious Diseases and Clinical Microbiology, Ministry of Health Okmeydani Training and Research Hospital, Istanbul, Turkey Objective: The aim of this study is to analyze the expenditures related to the use of antifungal drugs
Gedik H
doaj
Magnetic Textiles: A Review of Materials, Fabrication, Properties, and Applications
Magnetic textiles (M‐textiles) are emerging as a programmable materials platform that merges magnetic matter with hierarchical textile structures. This article consolidates magnetic material classes, textile architectures, and fabrication and magnetization strategies, revealing structure–property–function relationships that govern magneto‐mechanical ...
Li Ke +3 more
wiley +1 more source

