Results 121 to 130 of about 3,376,929 (374)

Antimicrobial Activities and Mechanisms of Magnesium Oxide Nanoparticles (nMgO) against Pathogenic Bacteria, Yeasts, and Biofilms. [PDF]

, 2018
Magnesium oxide nanoparticle (nMgO) is a light metal based antimicrobial nanoparticle that can be metabolized and fully resorbed in the body. To take advantage of the antimicrobial properties of nMgO for medical use, it is necessary to determine the ...
Grelling, Nathaniel, Liu, Huinan, Nguyen, Nhu-Y Thi, Rosario, Romeo, Wetteland, Cheyann Lee   +4 more
core   +3 more sources

Alarming India‐wide phenomenon of antifungal resistance in dermatophytes: A multicentre study

Mycoses (Berlin), 2020
An alarming increase in recalcitrant dermatophytosis has been witnessed in India over the past decade. Drug resistance may play a major role in this scenario.
A. Ebert, M. Monod, K. Salamin, A. Burmester, S. Uhrlass, C. Wiegand, U. Hipler, C. Krüger, D. Koch, F. Wittig, S. Verma, A. Singal, Sanjeev Gupta, R. Vasani, A. Saraswat, R. Madhu, Saumya Panda, Anupam Das, M. Kura, Akshy Kumar, S. Poojary, S. Schirm, Y. Gräser, U. Paasch, P. Nenoff   +24 more
semanticscholar   +1 more source

Few‐Layered Conductive Graphene Foams for Electrical Transdifferentiation of Mesenchymal Stem Cells Into Schwann Cell‐Like Phenotypes

Advanced Healthcare Materials, EarlyView.
Few‐layered three dimansional conductive graphene foams are promising cytocompatible platforms to transdifferentiate mesenchymal stem cells into Schwann cell‐like phenotypes using electrical and microstructural cues. Applied electrical stimulation conditions resulted in activation of MAPK, neurotrphin and RAS signaling pathways that led to upregulation
Ekin G. Simsar, Peifu Cheng, Tugce Dogruel, Maxsam Donta, Juhyung Jung, Naomi A. Asante, Donald S. Sakaguchi, Surya K. Mallapragada, Piran R. Kidambi, Metin Uz   +9 more
wiley   +1 more source

Vertebrate Hosts as Islands: Dynamics of Selection, Immigration, Loss, Persistence, and Potential Function of Bacteria on Salamander Skin. [PDF]

, 2016
Skin bacterial communities can protect amphibians from a fungal pathogen; however, little is known about how these communities are maintained. We used a neutral model of community ecology to identify bacteria that are maintained on salamanders by ...
Harris, Reid N, Knight, Rob, Loudon, Andrew H, McKenzie, Valerie J, Parfrey, Laura Wegener, Schmidt, Thomas M, Van Treuren, William, Venkataraman, Arvind, Woodhams, Douglas C   +8 more
core   +2 more sources

Antifungal Resistance in Candida auris: Molecular Determinants

Antibiotics, 2020
Since Candida auris integrates strains resistant to multiple antifungals, research has been conducted focused on knowing which molecular mechanisms are involved. This review aims to summarize the results obtained in some of these studies.
M. G. Frías-De-León, R. Hernández-Castro, Tania Vite-Garín, R. Arenas, A. Bonifaz, L. Castañón-Olivares, G. Acosta-Altamirano, E. Martínez-Herrera   +7 more
semanticscholar   +1 more source

Bioengineered Pancreatic Cancer Immunosuppressive Microenvironment Models for Screening Immunotherapies

Advanced Healthcare Materials, EarlyView.
Bioengineering tumor‐stroma pancreatic cancer models with potential to emulate the native immunosuppressive tumor microenvironment. Cancer‐on‐a‐bead models exhibited higher relevance for screening immunotherapies and modulating the protumoral PDAC microenvironment. ABSTRACT Pancreatic cancer is notably resistant to treatment, primarily due to its dense
Maria V. Monteiro, Margarida Henriques‐Pereira, Bruno M. Neves, Vítor M. Gaspar, João F. Mano   +4 more
wiley   +1 more source

Azole Antifungal Resistance in Candida albicans and Emerging Non-albicans Candida Species

Frontiers in Microbiology, 2017
Within the limited antifungal armamentarium, the azole antifungals are the most frequent class used to treat Candida infections. Azole antifungals such as fluconazole are often preferred treatment for many Candida infections as they are inexpensive ...
D. Sanglard, E. Berkow, S. Whaley, E. Berkow, J. Rybak, A. Nishimoto, K. Barker, P. David Rogers   +7 more
semanticscholar   +1 more source

New Insights into Atonic Postpartum Hemorrhage: Animal Model Construction Based on Placental Nanodelivery Systems

Advanced Healthcare Materials, EarlyView.
This study develops a placenta‐targeted nanodelivery system co‐loading HMGB1 protein and the NLRP3 agonist nigericin to establish an animal model of atonic postpartum hemorrhage. The model accurately recapitulates clinical phenotypes, including prolonged labor and uterine contractility dysfunction, while revealing inflammatory activation in placental ...
Jiangxue Qu, Ruiqi Wu, Hai Jiang, Lian Chen, Yingying Tian, Shuai Zeng, Tongmin Liu, Cheng Zhao, Huifeng Shi, Xiaolong Liang, Yangyu Zhao   +10 more
wiley   +1 more source

A Review of Antifungal Resistance in West Africa

Borneo Journal of Pharmacy
Knowledge of local and regional antimicrobial resistance (AMR) is important for clinical decision-making. However, surveillance capacity for fungal infections let alone antifungal resistance is lacking throughout West Africa, and current antifungal ...
Abraham Bwalhuma Muhindo, Adamu Almustapha Aliero, Festo Mwebaze Syalhasha, Ibrahim Ntulume, Emmanuel Eilu, Martin Odoki, Joe Mutebi   +6 more
doaj   +1 more source

Evaluation of antifungal susceptibility testing in Candida isolates by Candifast and disk-diffusion method

Indian Journal of Pathology and Microbiology, 2014
With the increase in invasive fungal infections due to Candida species and resistance to antifungal therapy, in vitro antifungal susceptibility testing is becoming an important part of clinical microbiology laboratories.
Sidhartha Giri, Anupma Jyoti Kindo
doaj   +1 more source