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Antifungal Susceptibility Testing in Teaching Hospitals
Annals of Pharmacotherapy, 2003BACKGROUND: An assessment of antifungal susceptibility testing (AST) has not been conducted since the introduction of the National Committee for Clinical Laboratory Standards (NCCLS) M27-A document. OBJECTIVE: To determine AST ...
Manjunath P, Pai, Susan L, Pendland
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Antifungal Susceptibility Testing Methods
Current Drug Targets, 2005The number of systemically active antifungal agents has increased dramatically in recent years in response to the challenge of invasive mycoses. Additional work is needed to better understand the mechanisms of action of these agents as well as the mechanisms of resistance expressed by the fungal pathogens.
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Antifungal Agents and Antifungal Susceptibility Testing
20101 Systemic Antifungal Drugs in Current Use 2 Future Antifungal Drugs 3 Antifungal Susceptibility Testing 4 Methods of Susceptibility Testing Keywords: antifungal agents and antifungal susceptibility testing; systemic antifungal drugs in current use; antifungal mechanisms of action; lipid vehicles for polyenes; unique ...
Sanjay G. Revankar +2 more
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Antifungal Drug Susceptibility Testing
1989The continuing introduction of new antifungal drugs has increased the demand for methods of in vitro testing that can predict the effects of compounds in vivo. As with antibacterial drugs, tests designed to ascertain the minimum amount of drug needed to inhibit the growth of organisms in vitro (minimum inhibitory concentration, or MIC) have often been ...
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Antifungal Susceptibility Testing: A Primer for Clinicians
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 2012Antifungal susceptibility testing is not as commonly performed as antibacterial susceptibility testing. The methodology for detecting antifungal resistance is newer and requires different testing supplies that may not be readily available in a clinical laboratory setting. Breakpoints for molds are lacking.
Kristi M, Kuper +2 more
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Antifungal drug susceptibility testing
Mycopathologia, 1984The advent of new antifungal drugs provides clinicians with therapeutic options, and it is anticipated requests for fungal susceptibility testing in vitro will increase. Our own laboratory's experience indicates that results can be provided promptly even to distant medical centers.
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Antifungal susceptibility testing with dermatophytes
Mycoses, 1991Summary. The determination of the in vitro activity of antimycotics against dermatophytes has for long been considered as irrelevant from a practical point of view. Recently, however, this approach has been questioned. Various different tests such as agar diffusion test, agar dilution test and broth dilution test can be used for the determination of ...
Aletta Georgii, H. C. Korting
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Progress in Standardizing Antifungal Susceptibility Tests
Clinics in Laboratory Medicine, 1989In vitro tests of antifungal agents are receiving increasing attention as important procedures for the clinical laboratory. As antifungal agents proliferate, it will become more and more valuable to have available antifungal susceptibility tests to aid in treatment selections based on the specific activities of different drugs against a patient's own ...
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Etest for antifungal susceptibility testing of yeasts
Diagnostic Microbiology and Infectious Disease, 1994Comparison [+/- 1 dilution between minimum inhibitory concentrations (MICs)] of fluconazole and flucytosine Etest MICs of 10 candidate quality control yeast isolates and 78 clinical isolates demonstrated good agreement (> or = 90%) with the reference method (National Committee for Clinical Laboratory Standards document M27-P).
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Antifungal Susceptibility Testing and Therapy
2009The development of new therapies to treat fatal diseases is creating an increasing number of patients who have predisposing factors for infections by opportunistic yeasts. The rise in the prevalence of fungal infections has been the drive to develop and license several new antifungal agents such as new formulations of polyenes, new triazole agents and ...
Manuel Cuenca-Estrella +1 more
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