Results 211 to 220 of about 3,341,399 (277)

Pyrene‐linked heterocyclic pyrazoles: Synthesis, antimicrobial screening, and in silico molecular insights

open access: yesSmart Molecules, EarlyView.
A series of novel pyrene‐linked heterocyclic pyrazoles were synthesized and structurally characterized. The compounds were evaluated for antimicrobial activity against selected bacterial and fungal strains, showing promising inhibitory effects. Molecular docking studies provided insights into binding interactions and structure–activity relationships ...
Dinkal V. Kasundra, Paresh N. Patel
wiley   +1 more source

Agricultural Fungicide Mancozeb in Leaf Litter Enhances Survival and Growth of Aedes aegypti (Diptera: Culicidae)

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Mancozeb is one of the most widely used agricultural fungicides, exhibiting strong efficacy against a broad spectrum of phytopathogenic fungi. However, its widespread application comes at the cost of environmental contamination. Here, we show the effects of Inga vera leaf litter contamination with Mancozeb on life‐history traits of Aedes ...
Heloise Restello Remus   +8 more
wiley   +1 more source

Evaluating Thiram‐Induced Embryotoxicity Using Integrated In Silico, In Vitro, and Transcriptomic Approaches

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Long‐term exposure to low‐dose food contact materials (FCMs) has raised concerns regarding developmental toxicity. In the present study, we prioritized FCMs with potential developmental toxicity using a weight‐of‐evidence computational model, which predicted 127 chemicals to be of high concern.
Chia‐Chi Ho   +7 more
wiley   +1 more source

Establishment of a Human Cell‐Based In Vitro Test System for Investigating and Evaluating Cytotoxic and Immunomodulatory Effects of Indoor Mold

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Mold growth in damp indoor environments is a widespread problem associated with respiratory health effects, though causal mechanisms remain incompletely understood. We established a human cell‐based in vitro test system using bronchial epithelial cells (NuLi‐1) and macrophages (THP‐1) to assess inhalation toxicity and immunomodulatory effects ...
Anja Wolff   +8 more
wiley   +1 more source

A simple and reproducible 96-well plate-based method for the formation of fungal biofilms and its application to antifungal susceptibility testing

open access: yesNature Protocols, 2008
C. Pierce   +6 more
semanticscholar   +1 more source

Effect of Propylparaben on In Vitro Maturation of Porcine Oocytes and Embryo Development

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Parabens are synthetic chemicals that, due to their antibacterial and fungicidal effects, are widely used as preservatives in food, cosmetics, and personal care products, such as shampoos, hair conditioners, body creams, soaps, deodorants, makeup, wet wipes, lotions, female hygiene products, and vaginal lubricants. Several years ago, they were
Elivier Núñez‐Macías   +10 more
wiley   +1 more source

Susceptibility Testing of Common and Uncommon Aspergillus Species against Posaconazole and Other Mold-Active Antifungal Azoles Using the Sensititre Method

open access: yesAntimicrobial Agents and Chemotherapy, 2017
Enrica Mello   +7 more
semanticscholar   +1 more source

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