Results 1 to 10 of about 2,461,321 (372)
Diverse Humoral Immune Responses in Younger and Older Adult COVID-19 Patients
mBio, 2021 As numerous viral variants continue to emerge in the coronavirus disease 2019 (COVID-19) pandemic, determining antibody reactivity to SARS-CoV-2 epitopes becomes essential in discerning changes in the immune response to infection over time.
Jennifer M. Sasson +14 more
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Microbiology Spectrum, 2021 The rapid worldwide spread of SARS-CoV-2 has accelerated research and development for controlling the COVID-19 pandemic. A multi-coronavirus protein microarray was created containing full-length proteins, overlapping protein fragments of various lengths,
David Camerini +22 more
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Frontiers in Immunology, 2022 In order to treat the alloimmunization platelet transfusion refractoriness (PTR), human leukocyte antigen (HLA)-type and/or human platelet antigen (HPA)-type matched platelets between donors and patients are usually used.
Jielin Wang +13 more
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Mathematical Modeling Insights into Improving CAR T cell Therapy for Solid Tumors: Antigen Heterogeneity and Bystander Effects [PDF]
npj Systems Biology and Applications, 10(1), 105 (2024), 2023 As an adoptive cellular therapy, Chimeric Antigen Receptor T-cell (CAR T-cell) therapy has shown remarkable success in hematological malignancies, but only limited efficacy against solid tumors. Compared with blood cancers, solid tumors present a unique set of challenges that ultimately neutralize the function of CAR T-cells.
arxiv +1 more source
Application efficiency of probiotics in poultry
Алматы технологиялық университетінің хабаршысы, 2021 Due to the growing demand for high-quality poultry and eggs in Kazakhstan, the transition to eco-friendly production is more urgent than ever. The use of probiotics in poultry farms can ensure product safety and economic efficiency. This article presents
N. Zh. Begdildayeva +3 more
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Vaccines, 2021 Murine dendritic cells, when pulsed with heat-killed Burkholderia pseudomallei and used to immunise naïve mice, have previously been shown to induce protective immunity in vivo. We have now demonstrated the in vitro priming of naïve human T cells against
Durga Reddi +9 more
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TruNeo: an integrated pipeline improves personalized true tumor neoantigen identification
BMC Bioinformatics, 2020 Background Neoantigen-based personal vaccines and adoptive T cell immunotherapy have shown high efficacy as a cancer treatment in clinical trials. Algorithms for the accurate prediction of neoantigens have played a pivotal role in such studies.
Yunxia Tang +8 more
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What are the challenges for implementing an “organic label” to camel milk?
Frontiers in Nutrition, 2023 Increasing demand for camel’s milk worldwide occurred in the context of the development of the organic sector in agriculture. The implementation of an organic label for camel milk has never been established. However, the creation of such a label faces to
Gaukhar Konuspayeva +5 more
doaj +1 more source
eLife, 2020 Tanzanian adult male volunteers were immunized by direct venous inoculation with radiation-attenuated, aseptic, purified, cryopreserved Plasmodium falciparum (Pf) sporozoites (PfSPZ Vaccine) and protective efficacy assessed by homologous controlled human
Flavia Camponovo +14 more
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Chimeric antigen receptor T cells for sustained remissions in leukemia.
New England Journal of Medicine, 2014 BACKGROUND Relapsed acute lymphoblastic leukemia (ALL) is difficult to treat despite the availability of aggressive therapies. Chimeric antigen receptor-modified T cells targeting CD19 may overcome many limitations of conventional therapies and induce ...
S. Maude +18 more
semanticscholar +1 more source