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Diverse Humoral Immune Responses in Younger and Older Adult COVID-19 Patients
As numerous viral variants continue to emerge in the coronavirus disease 2019 (COVID-19) pandemic, determining antibody reactivity to SARS-CoV-2 epitopes becomes essential in discerning changes in the immune response to infection over time.
Jennifer M. Sasson+14 more
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The rapid worldwide spread of SARS-CoV-2 has accelerated research and development for controlling the COVID-19 pandemic. A multi-coronavirus protein microarray was created containing full-length proteins, overlapping protein fragments of various lengths,
David Camerini+22 more
doaj +1 more source
In order to treat the alloimmunization platelet transfusion refractoriness (PTR), human leukocyte antigen (HLA)-type and/or human platelet antigen (HPA)-type matched platelets between donors and patients are usually used.
Jielin Wang+13 more
doaj +1 more source
Application efficiency of probiotics in poultry
Due to the growing demand for high-quality poultry and eggs in Kazakhstan, the transition to eco-friendly production is more urgent than ever. The use of probiotics in poultry farms can ensure product safety and economic efficiency. This article presents
N. Zh. Begdildayeva+3 more
doaj +1 more source
TruNeo: an integrated pipeline improves personalized true tumor neoantigen identification
Background Neoantigen-based personal vaccines and adoptive T cell immunotherapy have shown high efficacy as a cancer treatment in clinical trials. Algorithms for the accurate prediction of neoantigens have played a pivotal role in such studies.
Yunxia Tang+8 more
doaj +1 more source
Murine dendritic cells, when pulsed with heat-killed Burkholderia pseudomallei and used to immunise naïve mice, have previously been shown to induce protective immunity in vivo. We have now demonstrated the in vitro priming of naïve human T cells against
Durga Reddi+9 more
doaj +1 more source
What are the challenges for implementing an “organic label” to camel milk?
Increasing demand for camel’s milk worldwide occurred in the context of the development of the organic sector in agriculture. The implementation of an organic label for camel milk has never been established. However, the creation of such a label faces to
Gaukhar Konuspayeva+5 more
doaj +1 more source
An effective tumor vaccine vector that can rapidly display neoantigens is urgently needed. Outer membrane vesicles (OMVs) can strongly activate the innate immune system and are qualified as immunoadjuvants. Here, we describe a versatile OMV-based vaccine
Keman Cheng+18 more
semanticscholar +1 more source
Chimeric antigen receptor T cells for sustained remissions in leukemia.
BACKGROUND Relapsed acute lymphoblastic leukemia (ALL) is difficult to treat despite the availability of aggressive therapies. Chimeric antigen receptor-modified T cells targeting CD19 may overcome many limitations of conventional therapies and induce ...
S. Maude+18 more
semanticscholar +1 more source