FEBS Open Bio, EarlyView.In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley +1 more source
A Plant-Derived Antigen-Antibody Complex Induces Anti-Cancer Immune Responses by Forming a Large Quaternary Structure. [PDF]
Int J Mol Sci, 2020 Kim DS +7 more
europepmc +1 more source
A model for the differentiation of human natural killer cells. Studies on the in vitro activation of Leu-11+ granular lymphocytes with a natural killer-sensitive tumor cell, K562. [PDF]
, 1985 A subpopulation of low density granular lymphocytes that express the natural killer (NK) cell-associated Leu-11 antigen (IgG Fc receptor) were stimulated directly by coculture with an NK-sensitive tumor cell, K562.
Lanier, LL, Phillips, JH
core
Immune reactions in polysaccharide media. The composition of the antigen–antibody complexes in the precipitin reaction [PDF]
, 1969 Krister Hellsing
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Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies
Aging and Cancer, EarlyView.This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal +8 more
wiley +1 more source
Studies on the Role of Serotonin and Mast Cells in Anaphylaxis of the Mouse Produced with Soluble Antigen-Antibody Complexes [PDF]
, 1961 S. Tokuda, Russell S. Weiser
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Advanced Biology, Volume 9, Issue 3, March 2025.Yi‐Fei‐Jie‐Du‐Tang (YFJDT), a traditional Chinese medicine, has shown potential in lung cancer treatment by targeting key pathways. This study explores the mechanisms of YFJDT using bioinformatics, xenograft models, and A549 cells, demonstrating that YFJDT downregulates HIF1A, promotes ferroptosis, and inhibits epithelial‐mesenchymal transition (EMT ...
Shanshan Wang +6 more
wiley +1 more source
THE IN VIVO FORMATION AND FATE OF ANTIGEN-ANTIBODY COMPLEXES FORMED BY FRAGMENTS AND POLYPEPTIDE CHAINS OF RABBIT γG-ANTIBODIES [PDF]
, 1966 Hans L. Spiegelberg, William O. Weigle
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Advanced Biology, EarlyView.Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi +4 more
wiley +1 more source
The Formation of Soluble Complexes in the Region of Antibody Excess with Protein Antigens and Their Rabbit Antibodies [PDF]
, 1963 O Förster, William O. Weigle
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