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Influence of the administration route and dose on the expression and antibody responses of a reporter and avian influenza self-amplifying mRNA vaccine in poultry. [PDF]
Vet QSnoeck J +4 more
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Sub-cellular biochemistry, 2020
In vertebrates, immunoglobulins (Igs), commonly known as antibodies, play an integral role in the armamentarium of immune defense against various pathogens. After an antigenic challenge, antibodies are secreted by differentiated B cells called plasma cells.
A Brenda, Kapingidza +2 more
semanticscholar +5 more sources
In vertebrates, immunoglobulins (Igs), commonly known as antibodies, play an integral role in the armamentarium of immune defense against various pathogens. After an antigenic challenge, antibodies are secreted by differentiated B cells called plasma cells.
A Brenda, Kapingidza +2 more
semanticscholar +5 more sources
Immunoregulatory effects of a covalent antigen–antibody complex
Nature, 1979It is becoming increasingly clear that any specific immune response must be subject to a control mechanism of the same order of specificity. The basis of such specificity in control almost certainly lies in the antibodies themselves, whether free or cell bound.
Taylor, R B, Tite, J P, Manzo, C
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Stability of the Antigen-Antibody Complex
Bibliotheca haematologica, 2015J. Boyer
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Australia Antigen–Antibody Complexes
Nature, 1970BLUMBERG and his colleagues have published data on the relation of Australia antigen, Au(1), to hepatitis1,2. While existing antisera, either of human or rabbit sources3, frequently can be used to detect this antigen in patients with hepatitis by either immunodiffusion4 or complement fixation5 it is probable that the antigen is undetectable in some ...
I, Millman +3 more
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Simulations that capture antigen–antibody complexity
Nature Computational Science, 2022Abstract: Antigen-antibody prediction remains a complex computational challenge. Simulations with the new Absolut! package provide novel insights into the models and datasets tackling this problem.
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Analysis of Binding Modes of Antigen-Antibody Complexes by Molecular Mechanics Calculation
Journal of Chemical Information and Modeling, 2021Antibodies are one of the most important protein molecules in biopharmaceutics. Due to the recent advance in technology for producing monoclonal antibodies, many structural data are available on the antigen-antibody complexes.
Liang Qu +4 more
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Degenerate interfaces in antigen-antibody complexes
Journal of Molecular Biology, 2001In most of the work dealing with the analysis of protein-protein interfaces, a single X-ray structure is available or selected, and implicitly it is assumed that this structure corresponds to the optimal complex for this pair of proteins. However, we have found a degenerate interface in a high-affinity antibody-antigen complex: the two independent ...
Decanniere, Klaas +5 more
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THE NATURE OF AUSTRALIA ANTIGEN AND ITS RELATION TO ANTIGEN-ANTIBODY COMPLEX FORMATION
Journal of Experimental Medicine, 1971There is considerable data to support the hypothesis that Australia antigen is an infectious agent that causes hepatitis in man. (a) Association with acute viral hepatitis. (b) Association with chronic hepatitis.
B. S. Blumberg +3 more
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