Results 41 to 50 of about 1,301,436 (306)

Use of donor serum to prevent passive transfer of hyperacute rejection [PDF]

, 1994
Organ transplantation in presensitized recipients continues to be contraindicated for heart and kidney recipients due to the risk of hyperacute rejection, which has no known treatment at this time.
Burlingham, William J., Fechner, John H., Geissler, Edward K., Knechtle, Stuart J., Wang, Jue   +4 more
core   +1 more source

Use of poxvirus display to select antibodies specific for complex membrane antigens

mAbs, 2023
Antibody discovery against complex antigens is limited by the availability of a reproducible pure source of concentrated properly folded antigen. We have developed a technology to enable direct incorporation of membrane proteins such as GPCRs and into ...
Ernest S. Smith, Leslie A. Balch, Maria Scrivens, Shuying Shi, Wei Wang, Caroline D. Harvey, Angelica A. Cornelison, Malgorzata Gil-Moore, Renee A. Kirk, Loretta L. Mueller, Richard L. Hall, Alan P. Howell, Christine A. Reilly, Jessica M. Mayer, Francis G. Murante, Kari A Viggiani, Elaine M. Gersz, Holm Bussler, Madeleine R. Keefe, Elizabeth E. Evans, Mark J. Paris, Maurice Zauderer   +21 more
doaj   +1 more source

Expression of thyroglobulin on follicular dendritic cells of thyroid mucosa-associated lymphoid tissue (MALT) lymphoma [PDF]

, 2009
Reportedly, thyroid mucosa-associated lymphoid tissue (MALT) lymphoma is closely associated with Hashimoto's thyroiditis. However, it remains unknown which antigen is closely associated with thyroid MALT lymphoma.
Akagi, Tadaatsu, Kobayashi, Keita, Mannami, Tomohiko, Miyake, Takayoshi, Munemasa, Mitsuru, Sakugawa, Sumie Takase, Shinagawa, Katsuji, Tanimoto, Mitsune, Yoshino, Tadashi   +8 more
core   +1 more source

A novel interdigitated capacitor based biosensor for detection of cardiovascular risk marker [PDF]

, 2009
C-reactive protein (CRP) is a potential biomarker whose elevated levels in humans determine cardiovascular disease risk and inflammation. In this study, we have developed a novel capacitive biosensor for detection of CRP-antigen using capacitor with ...
Davidson, Jimmy L., Gürbüz, Yaşar, Kang, Weng P., Qureshi, Anjum   +3 more
core   +1 more source

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel, Patricia Pastura, Joshua P. Scallan, Timothy D. Le Cras   +3 more
wiley   +1 more source

Structural Features of Antibody-Peptide Recognition

Frontiers in Immunology, 2022
Antibody recognition of antigens is a critical element of adaptive immunity. One key class of antibody-antigen complexes is comprised of antibodies targeting linear epitopes of proteins, which in some cases are conserved elements of viruses and pathogens
Jessica H. Lee, Rui Yin, Rui Yin, Gilad Ofek, Gilad Ofek, Brian G. Pierce, Brian G. Pierce, Brian G. Pierce   +7 more
doaj   +1 more source

A General Theory for Direct Quantitative Analysis of Antigen [PDF]

, 2012
A theory for direct quantitative analysis of an antigen is proposed. It is based on a potential homogenous immunoreaction system. It establishes an equation to describe the concentration change of the antigen and antibody complex.
Gan, Feng, Liu, Langxia, Liu, Xiaohui, Ye, Gang   +3 more
core  

Protein-Protein Docking with F2Dock 2.0 and GB-Rerank [PDF]

, 2013
Rezaul Chowdhury is with UT Austin; Muhibur Rasheed is with UT Austin; Maysam Moussalem is with UT Austin; Donald Keidel is with The Scripps Research Institute; Arthur Olson is with The Scripps Research Institute; Michel Sanner is with The Scripps ...
Bajaj, Chandrajit, Chowdhury, Rezaul, Keidel, Donald, Moussalem, Maysam, Olson, Arthur, Rasheed, Muhibur, Sanner, Michel   +6 more
core   +4 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

SnugDock: paratope structural optimization during antibody-antigen docking compensates for errors in antibody homology models.

PLoS Computational Biology, 2010
High resolution structures of antibody-antigen complexes are useful for analyzing the binding interface and to make rational choices for antibody engineering.
Aroop Sircar, Jeffrey J Gray
doaj   +1 more source