Neutralization of Diverse Human Cytomegalovirus Strains Conferred by Antibodies Targeting Viral gH/gL/pUL128-131 Pentameric Complex [PDF]
Human cytomegalovirus (HCMV) is the leading cause of congenital viral infection, and developing a prophylactic vaccine is of high priority to public health.
Adler, Stuart P. +19 more
core +3 more sources
The present study was conducted to predict T-cell epitopes of the antigen 85 complex capable of stimulating antibody generation by using immunoinformatics approaches.
YOGY SIMANJUNTAK
doaj +1 more source
Antibodies for immunolabeling by light and electron microscopy : not for the faint hearted [PDF]
Reliable antibodies represent crucial tools in the arsenal of the cell biologist and using them to localize antigens for immunocytochemistry is one of their most important applications.
Griffiths, Gareth, Lucocq, John Milton
core +1 more source
Involvement of Mhc Loci in immune responses that are not Ir-gene-controlled [PDF]
Twenty-nine randomly chosen, soluble antigens, many of them highly complex, were used to immunize mice of two strains, C3H and B10.RIII. Lymphnode cells from the immunized mice were restimulated in vitro with the priming antigens and the proliferative ...
C. J. Kreo +28 more
core +1 more source
VNARs: An Ancient and Unique Repertoire of Molecules That Deliver Small, Soluble, Stable and High Affinity Binders of Proteins [PDF]
Peer reviewedPublisher ...
Clem +4 more
core +3 more sources
Vaccine-induced immune thrombotic thrombocytopenia: Updates in pathobiology and diagnosis
Coronavirus disease 2019 (COVID-19) is a viral respiratory infection caused by the severe acute respiratory syndrome virus (SARS-CoV-2). Vaccines that protect against SARS-CoV-2 infection have been widely employed to reduce the incidence of symptomatic ...
Stefan D. Jevtic +10 more
doaj +1 more source
AbAgym: a well-curated dataset for the mutational analysis of antibody–antigen complexes
With monoclonal antibodies becoming one of the largest classes of biopharmaceuticals, it is important to have curated data to train computational models that can accelerate their design.
Gabriel Cia +4 more
doaj +1 more source
Background The current therapeutic antibodies and chimeric antigen receptor (CAR) T cells are capable of recognizing surface antigens, but not of intracellular proteins, thus limiting the target coverage for drug development.
Xin Liu +14 more
doaj +1 more source
Reversal of terminal differentiation and control of DNA replication [PDF]
DNA replication in mammalian cells occurs in discrete nuclear foci. Here we show that terminally differentiated myotubes can be induced to reenter S phase and show the same pattern of replication foci as cycling cells.
Cardoso, M. Cristina +2 more
core +1 more source
THE STRUCTURE OF ANTIGEN-ANTIBODY COMPLEXES [PDF]
Negatively stained aggregates of antigen (polyoma or verruca vulgaris virus) and antibody (from rabbit or goat) were examined in the electron microscope. The antibody molecules appeared as cylindrical rods (often, but not always, showing a beaded appearance) with a long axis of 250 to 270 A and a short axis of 35 to 40 A.
June Almeida +2 more
openaire +1 more source

