Results 31 to 40 of about 1,112,551 (312)

Development of a sensitive detection method of cancer biomarkers in human serum (75%) using a quartz crystal microbalance sensor and nanoparticles amplification system [PDF]

, 2010
A simple and sensitive sensor method for cancer biomarkers [prostate specific antigen (PSA) and PSA-alpha 1-antichymotrypsin (ACT) complex] analysis was developed, to be applied directly with human serum (75%) by using antibody modified quartz crystal
Uludag, Yildiz, Tothill, Ibtisam E.
core   +1 more source

T-cell Epitopes of Mycobacterium tuberculosis Antigen 85 Complex Potential for Generating Antibody: an Immunoinformatics Study

Microbiology Indonesia, 2010
The present study was conducted to predict T-cell epitopes of the antigen 85 complex capable of stimulating antibody generation by using immunoinformatics approaches.
YOGY SIMANJUNTAK
doaj   +1 more source

Antibodies for immunolabeling by light and electron microscopy : not for the faint hearted [PDF]

, 2014
Reliable antibodies represent crucial tools in the arsenal of the cell biologist and using them to localize antigens for immunocytochemistry is one of their most important applications.
Lucocq, John Milton, Griffiths, Gareth
core   +1 more source

Complete, long-lasting protection against malaria of mice primed and boosted with two distinct viral vectors expressing the same plasmodial antigen. [PDF]

, 2001
We report that complete protection against malaria and total inhibition of liver stage development and parasitemia was obtained in 100% of BALB/c mice primed with a replication-defective recombinant adenovirus expressing the circumsporozoite (CS) protein
Oscar Bruña-Romero, Gloria González-Aseguinolaza, Ruth S. Nussenzweig, Tsuji, M, González-Aseguinolaza, G, Julius C. R. Hafalla, Bruña-Romero, O, Hafalla, JC, Nussenzweig, RS, Moriya Tsuji   +9 more
core   +1 more source

Vaccine-induced immune thrombotic thrombocytopenia: Updates in pathobiology and diagnosis

Frontiers in Cardiovascular Medicine, 2022
Coronavirus disease 2019 (COVID-19) is a viral respiratory infection caused by the severe acute respiratory syndrome virus (SARS-CoV-2). Vaccines that protect against SARS-CoV-2 infection have been widely employed to reduce the incidence of symptomatic ...
Stefan D. Jevtic, Donald M. Arnold, Donald M. Arnold, Donald M. Arnold, Dimpy Modi, Dimpy Modi, Nikola Ivetic, Anna-Lise Bissola, Anna-Lise Bissola, Ishac Nazy, Ishac Nazy   +10 more
doaj   +1 more source

Immune-Complex Mimics as a Molecular Platform for Adjuvant-Free Vaccine Delivery

, 2013
Protein-based vaccine development faces the difficult challenge of finding robust yet non-toxic adjuvants suitable for humans. Here, using a molecular engineering approach, we have developed a molecular platform for generating self-adjuvanting immunogens
Stylianou, E, Gil Reynolds Diogo, Reljic Rajko, Matthew J Paul, Pepponi Ilaria, Ma Julian K.-C., Julian K.-C. Ma, Drake, PM, Diogo Gil Reynolds, Drake Pascal M. W., Matthew J. Paul, Pepponi, I, Pascal M. W. Drake, Pascal M W Drake, van Dolleweerd Craig, Diogo, GR, Elena Stylianou, Craig van Dolleweerd, Rajko Reljic, Julian K-C Ma, Reljic, R, Ilaria Pepponi, van Dolleweerd, C, Paul Matthew J., Stylianou Elena, Ma, JK, Paul, MJ   +26 more
core   +1 more source

A DNA vaccine construct incorporating intercellular trafficking and intracellular targeting motifs effectively primes and induces memory B and T cell responses in outbred animals [PDF]

, 2007
We developed a vaccine construct in which a BVP22 domain and an invariant-chain major histocompatibility complex class II-targeting motif capable of enhancing dendritic cell antigen uptake and presentation were fused to a sequence encoding a B- and T ...
Palmer, Guy H, Zhuang, Yan, Mwangi, W, Howard, CJ, Aida, Yoko, Hunter, Beverly J, Splitter, Gary A, Brown, WC, Palmer, GH, Hunter, BJ, Aida, Y, Davies, Christopher J, Brown, Wendy C, Davies, CJ, Mwangi, Waithaka, Splitter, GA, Zhuang, Y, Hope, Jayne; id_orcid, Howard, Chris J, Hope, Jayne C   +19 more
core   +1 more source

AbAgym: a well-curated dataset for the mutational analysis of antibody–antigen complexes

mAbs
With monoclonal antibodies becoming one of the largest classes of biopharmaceuticals, it is important to have curated data to train computational models that can accelerate their design.
Gabriel Cia, Dong Li, Simón Poblete, Marianne Rooman, Fabrizio Pucci   +4 more
doaj   +1 more source

Development of a TCR-like antibody and chimeric antigen receptor against NY-ESO-1/HLA-A2 for cancer immunotherapy

Journal for ImmunoTherapy of Cancer, 2022
Background The current therapeutic antibodies and chimeric antigen receptor (CAR) T cells are capable of recognizing surface antigens, but not of intracellular proteins, thus limiting the target coverage for drug development.
Xin Liu, Yang Du, Ningyan Zhang, Zhiqiang An, Wei Xiong, Yixiang Xu, Bingnan Yin, Yuqian Huang, Junjun Chu, Changsheng Xing, Chen Qian, Tianhao Duan, Helen Y Wang, John S. Yu, Rongfu Wang   +14 more
doaj   +1 more source

Production, characterization, and antigen specificity of recombinant 62-71-3, a candidate monoclonal antibody for rabies prophylaxis in humans

, 2013
Rabies kills many people throughout the developing world every year. The murine monoclonal antibody (mAb) 62-71-3 was recently identified for its potential application in rabies postexposure prophylaxis (PEP).
Both, L, Bulmer-Thomas, B., Banyard, AC, Selden, D., Altmann, F, Craig van Dolleweerd (406086), David Selden (4911475), Selden, D, Ashley C Banyard (16267520), Both, L., Banyard, A.C., Edward Wright (4468198), Bulmer-Thomas, B, Fooks, AR, Friedrich Altmann (33138), Wright, E, van Dolleweerd, C., Fooks, A.R., Ma, J.K.C., Julian K C Ma (16267529), Leonard Both (16267517), van Dolleweerd, C, Ma, JK, Wright, E., Altmann, F., Anthony R Fooks (16267526), Bianca Bulmer-Thomas (16267523)   +26 more
core   +1 more source