Results 91 to 100 of about 416,035 (333)

Antigen Presentation by Spleen Dendritic Cells

Journal of Investigative Dermatology, 1985
It is now recognized that dendritic cells (DC) isolated from mouse spleen play an important role in activating T lymphocytes. These DC, which show many similarities to veiled cells found in the paracortical regions of spleen and lymph node, may be closely related to the epidermal Langerhans cells.
Geoffrey H. Sunshine, Tamara J. Mitchell
openaire   +3 more sources

Current status of multiple antigen-presenting peptide vaccine systems: Application of organic and inorganic nanoparticles

Chemistry Central Journal, 2011
Many studies are currently investigating the development of safe and effective vaccines to prevent various infectious diseases. Multiple antigen-presenting peptide vaccine systems have been developed to avoid the adverse effects associated with ...
Taguchi Hiroaki, Fujita Yoshio
doaj   +1 more source

MAVS Is essential for primary CD4 + T cell immunity but not for recall T cell responses following an attenuated West Nile virus infection [PDF]

, 2017
The use of pathogen recognition receptor (PRR) agonists and the molecular mechanisms involved have been the major focus of research in individual vaccine development.
Barrett, Alan D, Diamond, Michael S, Fang, Rong, Gale, Michael, Jr, Lazear, Helen M, Li, Li, Luo, Huanle, Paessler, Slobodan, Peng, Bi-Hung, Wang, Tian, Winkelmann, Evandro, Xie, Guorui   +11 more
core   +3 more sources

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source

The Role of Langerhans Cells in Antigen Presentation

Journal of Investigative Dermatology, 1985
Epidermal Langerhans cells are dendritic bone marrow-derived cells which synthesize and express Ia antigens. During the past decade, in vitro studies have demonstrated that they play a critical role in the induction of many types of T-cell responses.
Masafumi Iijima, Tetsuo Tsuchida, Kevin D. Cooper, Stephen I. Katz   +3 more
openaire   +3 more sources

Corrigendum: Recent advances in antigen targeting to antigen-presenting cells in veterinary medicine

Frontiers in Immunology, 2023
Edgar Alonso Melgoza-González, Lorena Bustamante-Córdova, Jesús Hernández   +2 more
doaj   +1 more source

Microbial antigens-loaded myeloma cells enhance Th2 cell proliferation and myeloma clonogenicity via Th2–myeloma cell interaction

BMC Cancer, 2019
Background Myeloma cells retain B cell functions, considered to be potential antigen presenting cells, yet there is little information regarding promoting Th2 cell proliferation or the direct effects to myeloma on the Th2 cells stimulated by microbial ...
Faqing Tian, Bo Lu, Ziren Chen, Junru Liu, Delan Ji, Juheng Li, Meiqin Tang, Wei Zhu, Juan Li   +8 more
doaj   +1 more source

Antigen presentation by hapten-specific B lymphocytes. I. Role of surface immunoglobulin receptors. [PDF]

, 1984
The present study examines the ability of hapten-specific murine splenic B lymphocytes to present hapten-proteins to carrier-specific T cell hybridomas.
Abbas, AK, Benacerraf, B, Rock, KL
core  

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

Development of a new protocol for 2-day generation of mature dendritic cells from human monocytes

Biological Procedures Online, 2003
We developed a new 2-day protocol for the generation of dendritic cells (DCs) from human monocytes in vitro. First, we demonstrated that 24 hours of culture with GM-CSF and IL-4 are sufficient to generate immature DCs capable of antigen uptake.
Obermaier Bianca, Dauer Marc, Herten Jan, Schad Katharina, Endres Stefan, Eigler Andreas   +5 more
doaj   +1 more source