Results 111 to 120 of about 2,747,893 (386)

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

A novel tissue culture method to produce professional antigen-presenting cells from rainbow trout in vitro

Comparative Immunology Reports
In this study, we describe a tissue culture method to identify and produce large quantities of professional antigen presenting cells (pAPCs) including dendritic cells (DCs) using fin explant cultures from rainbow trout.
Nguyen T. K. Vo, PhD, Lital Sever, PhD, Brian Dixon, PhD, Niels C. Bols, PhD   +3 more
doaj   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Myosin IIa Promotes Antibody Responses by Regulating B Cell Activation, Acquisition of Antigen, and Proliferation

Cell Reports, 2018
Summary: B cell responses are regulated by antigen acquisition, processing, and presentation to helper T cells. These functions are thought to depend on contractile activity of non-muscle myosin IIa.
Robbert Hoogeboom, Elizabeth M. Natkanski, Carla R. Nowosad, Dessislava Malinova, Rajesh P. Menon, Antonio Casal, Pavel Tolar   +6 more
doaj   +1 more source

ETEC colonisation factors disrupt the antigen presenting capacity of porcine intestinal dendritic cells [PDF]

, 2012
Enterotoxigenic E. coli (ETEC) are not only a major cause of diarrhoea in travellers to and children in developing countries, but also cause neonatal and postweaning diarrhoea in piglets, leading to a reduced feed conversion and a higher mortality rate ...
Baert, Kim, Devriendt, Bert, Luo, Yu
core  

Deletion of Antigen-Presenting Cells in Lipopolysaccharide-Induced Acute Kidney Injury (AKI) Affects the Exacerbation and Repair in AKI [PDF]

, 2022
Jinhai Li, Yuji Nozaki, Hiroki AKAZAWA, Kazuya Kishimoto, Koji Kinoshita, Itaru Matsumura   +5 more
openalex   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Corrigendum: Recent advances in antigen targeting to antigen-presenting cells in veterinary medicine

Frontiers in Immunology, 2023
Edgar Alonso Melgoza-González, Lorena Bustamante-Córdova, Jesús Hernández   +2 more
doaj   +1 more source

Current status of multiple antigen-presenting peptide vaccine systems: Application of organic and inorganic nanoparticles

Chemistry Central Journal, 2011
Many studies are currently investigating the development of safe and effective vaccines to prevent various infectious diseases. Multiple antigen-presenting peptide vaccine systems have been developed to avoid the adverse effects associated with ...
Taguchi Hiroaki, Fujita Yoshio
doaj   +1 more source

Influenza and memory T cells : how to awake the force [PDF]

, 2016
Annual influenza vaccination is an effective way to prevent human influenza. Current vaccines are mainly focused on eliciting a strain-matched humoral immune response, requiring yearly updates, and do not provide protection for all vaccinated individuals.
Glezen, Hartshorn, Hufford, Jin, Jordan, Luo, Mosmann, Razvi, Topham, Topham, Topham, Von Andrian, Wijburg   +12 more
core   +3 more sources