Results 121 to 130 of about 2,709,177 (395)

Corrigendum: Recent advances in antigen targeting to antigen-presenting cells in veterinary medicine

Frontiers in Immunology, 2023
Edgar Alonso Melgoza-González, Lorena Bustamante-Córdova, Jesús Hernández   +2 more
doaj   +1 more source

A novel tissue culture method to produce professional antigen-presenting cells from rainbow trout in vitro

Comparative Immunology Reports
In this study, we describe a tissue culture method to identify and produce large quantities of professional antigen presenting cells (pAPCs) including dendritic cells (DCs) using fin explant cultures from rainbow trout.
Nguyen T. K. Vo, PhD, Lital Sever, PhD, Brian Dixon, PhD, Niels C. Bols, PhD   +3 more
doaj   +1 more source

The Role of Langerhans Cells in Antigen Presentation

Journal of Investigative Dermatology, 1985
Epidermal Langerhans cells are dendritic bone marrow-derived cells which synthesize and express Ia antigens. During the past decade, in vitro studies have demonstrated that they play a critical role in the induction of many types of T-cell responses.
Masafumi Iijima, Tetsuo Tsuchida, Kevin D. Cooper, Stephen I. Katz   +3 more
openaire   +3 more sources

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

Control of RelB during dendritic cell activation integrates canonical and noncanonical NF-κB pathways. [PDF]

, 2012
The NF-κB protein RelB controls dendritic cell (DC) maturation and may be targeted therapeutically to manipulate T cell responses in disease. Here we report that RelB promoted DC activation not as the expected RelB-p52 effector of the noncanonical NF-κB ...
Asagiri, Masataka, Davis-Turak, Jeremy, Fagerlund, Riku, Hoffmann, Alexander, Huang, Jenny Q, Kearns, Jeffrey D, Macal, Monica, Ponomarenko, Julia, Shih, Vincent F-S, Yu, Tony, Zuniga, Elina I   +10 more
core   +2 more sources

Targeting dendritic cells in pancreatic ductal adenocarcinoma

Cancer Cell International, 2018
Dendritic cells (DC) are an integral part of the tumor microenvironment. Pancreatic cancer is characterized by reduced number and function of DCs, which impacts antigen presentation and contributes to immune tolerance.
Anton Deicher, Roland Andersson, Bobby Tingstedt, Gert Lindell, Monika Bauden, Daniel Ansari   +5 more
doaj   +1 more source

Mesothelial cell-derived antigen-presenting cancer-associated fibroblasts induce expansion of regulatory T cells in pancreatic cancer.

Cancer Cell, 2022
Huocong Huang, Zhaoning Wang, Yuqing Zhang, R. Pradhan, Debolina Ganguly, Raghav Chandra, Gilbert Z Murimwa, Steven Wright, Xiaowu Gu, R. Maddipati, Sören Müller, Shannon J. Turley, R. Brekken   +12 more
semanticscholar   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

Development of a new protocol for 2-day generation of mature dendritic cells from human monocytes

Biological Procedures Online, 2003
We developed a new 2-day protocol for the generation of dendritic cells (DCs) from human monocytes in vitro. First, we demonstrated that 24 hours of culture with GM-CSF and IL-4 are sufficient to generate immature DCs capable of antigen uptake.
Obermaier Bianca, Dauer Marc, Herten Jan, Schad Katharina, Endres Stefan, Eigler Andreas   +5 more
doaj   +1 more source

Antigen-Presenting Cells: Professionals and amateurs [PDF]

Current Biology, 1995
Professional antigen-presenting cells, notably dendritic cells, play a key role in stimulating naive T cells--but nonprofessional antigen-presenting cells, such as fibroblasts, may also contribute to this process.
openaire   +2 more sources