Results 171 to 180 of about 416,035 (333)

Human dermal fibroblasts present tetanus toxoid antigen to antigen-specific T cell clones. [PDF]

, 1985
Dale T. Umetsu, Jordan S. Pober, Haifa H. Jabara, Walter Fiers, Edmond J. Yunis, Steven J. Burakoff, Carol Shoshkes Reiss, Raif S. Geha   +7 more
openalex   +1 more source

Evaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing

Molecular Oncology, EarlyView.
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef, Hana Barhom, Sumit Chatterji, Netta Hecht, Oran Warhaftig, Iris Kamer, Oranit Zadok, Jair Bar, Limor Broday, Amir Onn, Michael Peled   +10 more
wiley   +1 more source

Novel antigen-presenting cell imparts T_reg-dependent tolerance to gut microbiota. [PDF]

Nature, 2022
Akagbosu B, Tayyebi Z, Shibu G, Paucar Iza YA, Deep D, Parisotto YF, Fisher L, Pasolli HA, Thevin V, Elmentaite R, Knott M, Hemmers S, Jahn L, Friedrich C, Verter J, Wang ZM, van den Brink M, Gasteiger G, Grünewald TGP, Marie JC, Leslie C, Rudensky AY, Brown CC.   +22 more
europepmc   +1 more source

Mouse spleen dendritic cells present soluble antigens to antigen-specific T cell hybridomas. [PDF]

, 1983
Geoffrey H. Sunshine, Daniel P. Gold, Henry H. Wortis, Philippa Marrack, John W. Kappler   +4 more
openalex   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

A novel tissue culture method to produce professional antigen-presenting cells from rainbow trout in vitro

Comparative Immunology Reports
In this study, we describe a tissue culture method to identify and produce large quantities of professional antigen presenting cells (pAPCs) including dendritic cells (DCs) using fin explant cultures from rainbow trout.
Nguyen T. K. Vo, PhD, Lital Sever, PhD, Brian Dixon, PhD, Niels C. Bols, PhD   +3 more
doaj  

Next-generation pathology detection of T cell-antigen-presenting cell immune synapses in human liver allografts. [PDF]

Hepatology, 2023
Wood-Trageser MA, Lesniak D, Gambella A, Gambella A, Golnoski K, Feng S, Bucuvalas J, Sanchez-Fueyo A, Demetris AJ.   +8 more
europepmc   +1 more source

Antigen-reactive T cell clones. II. Unique homozygous and (high responder x low responder)F1 hybrid antigen-presenting determinants detected using poly(Tyr, Glu)-poly D, L-Ala--poly Lys-reactive T cell clones. [PDF]

, 1981
Masao Kimoto, C. Garrison Fathman
openalex   +1 more source

Endoglin mediates the tumor‐ and metastasis‐promoting traits of stromal myofibroblasts in human breast carcinomas

Molecular Oncology, EarlyView.
Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo, Yoshihiro Mezawa, Zixu Wang, Ahmet Acar, Yasuhiko Ito, Atsushi Takano, Yohei Miyagi, Tomoyuki Yokose, Toshinari Yamashita, Yataro Daigo, Takuya Shirakihara, Akira Orimo   +11 more
wiley   +1 more source

Antigen presenting cell response to polysaccharide A is characterized by the generation of anti-inflammatory macrophages. [PDF]

Glycobiology, 2022
Zhou JY, Zhou D, Telfer K, Reynero K, Jones MB, Hambor J, Cobb BA.   +6 more
europepmc   +1 more source