Cotransfer of the Eαd and Aβd genes into L cells results in the surface expression of a functional mixed-isotype Ia molecule [PDF]
, 1986 Ia molecules play a key role in antigen recognition by T lymphocytes. To analyze the structural features of the individual α and β chains relevant to the assembly of intact Ia molecules, mouse fibroblasts were contransfected with various combinations of ...
Hood, Leroy +3 more
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Immunostimulatory effects of marine algae extracts on in vitro antigen-presenting cell activation and in vivo immune cell recruitment. [PDF]
Food Sci Nutr, 2023 Ho TL +6 more
europepmc +1 more source
Membrane Ia expression and antigen-presenting accessory cell function of L cells transfected with class II major histocompatibility complex genes. [PDF]
, 1984 Michael A. Norcross +3 more
openalex +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Presentation of exogenous protein antigens by dendritic cells to T cell clones. Intact protein is presented best by immature, epidermal Langerhans cells. [PDF]
, 1989 Nikolaus Romani +7 more
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Molecular Oncology, EarlyView.Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source
Proteomic analyses of smear-positive/negative tuberculosis patients uncover differential antigen-presenting cell activation and lipid metabolism. [PDF]
Front Cell Infect Microbiol, 2023 Ju Y +14 more
europepmc +1 more source
T cell priming in vivo: a major role for B cells in presenting antigen to T cells in lymph nodes. [PDF]
, 1987 Yacov Ron, Jonathan Sprent
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Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
(Not) Home alone: Antigen presenting cell - T Cell communication in barrier tissues. [PDF]
Front Immunol, 2022 Neuwirth T, Knapp K, Stary G.
europepmc +1 more source