Results 11 to 20 of about 2,709,177 (395)
T cell antigen discovery via Signaling and Antigen presenting Bifunctional Receptors [PDF]
Nature Methods, 2019 CD8+ T cells recognize and eliminate tumors in an antigen-specific manner. Despite progress in characterizing the antitumor T cell repertoire and function, the identification of target antigens remains a challenge.
Alok V. Joglekar +11 more
semanticscholar +6 more sources
Recent advances in antigen targeting to antigen-presenting cells in veterinary medicine
Frontiers in Immunology, 2023 Advances in antigen targeting in veterinary medicine have gained traction over the years as an alternative approach for diseases that remain a challenge for traditional vaccines.
Edgar Alonso Melgoza-González +2 more
doaj +1 more source
bioRxiv, 2021 Multiple recent single cell RNA sequencing (scRNA-seq) studies have identified a unique cancer-associated fibroblast (CAF) population in pancreatic ductal adenocarcinoma (PDA) called antigen-presenting CAFs (apCAFs).
Huocong Huang +3 more
semanticscholar +1 more source
A Comparative Immunohistochemical Analysis of Langerhans Cells in Oral Mucosa, Oral Lichen Planus and Oral Squamous Cell Carcinoma [PDF]
Journal of Clinical and Diagnostic Research, 2015 Background: Langerhans cells (LCs) are immunocompetent cells resident within oral mucosa which, together with intraepithelial lymphocytes, play a role in mucosal defence.
Aruna Kumari Maloth +5 more
doaj +1 more source
Effect of Cellular-Based Artificial Antigen Presenting Cells Expressing ICOSL, in T-cell Subtypes Differentiation and Activation [PDF]
Advanced Pharmaceutical Bulletin, 2021 Purposes: Effective and selective T-cell activation and proliferation during the T-cell expansion phase of a cellular adoptive immunotherapy method, challenging because recent studies revealed the importance of each subtype of T-cells in different ...
Mehdi Talebi +4 more
doaj +1 more source
Tumor Antigen Presentation by Dermal Antigen-Presenting Cells [PDF]
Journal of Investigative Dermatology, 2000 Several phenotypes of antigen-presenting cells are present in the dermis, where they presumably function to present encountered antigens for immune responses. This study examined the ability of dermal antigen-presenting cells to present tumor-associated antigens for the induction of in vivo antitumor immunity.
Edward Miranda +8 more
openaire +3 more sources
Antigen Presentation by Vascular Cells [PDF]
Frontiers in Immunology, 2017 Antigen presentation by cells of the vessel wall may initiate rapid and localized memory immune responses in peripheral tissues. Peptide antigens displayed on major histocompatibility complex (MHC) molecules on the surface of endothelial cells (ECs) can be recognized by T cell receptors on circulating effector memory T cells (TEM), triggering both ...
Rebecca Liu +3 more
openaire +4 more sources
Antigen-Presenting Cells and Antigen Presentation in Tertiary Lymphoid Organs [PDF]
Frontiers in Immunology, 2016 Tertiary lymphoid organs (TLOs) form in territorialized niches of peripheral tissues characterized by the presence of antigens; however, little is known about mechanism(s) of antigen handling by ectopic lymphoid structures. In this mini review, we will discuss the role of antigen-presenting cells and mechanisms of antigen presentation in TLOs ...
Catherine Hughes +5 more
openaire +7 more sources
Antigen presentation to B cells [PDF]
F1000 Biology Reports, 2010 B cells are capable of mounting responses to a bewildering range of potentially pathogenic antigens through the production of high-affinity antibodies and the establishment of immunological memory. Thus, regulated B-cell activation is critical for protection against a variety of bacterial and viral infections, as well as cancers.
Facundo D. Batista, Naomi E. Harwood
openaire +3 more sources
Evasion of Immunological Memory by S. aureus Infection: Implications for Vaccine Design
Frontiers in Immunology, 2021 Recurrent S. aureus infections are common, suggesting that natural immune responses are not protective. All candidate vaccines tested thus far have failed to protect against S.
Omid Teymournejad +2 more
doaj +1 more source