Results 201 to 210 of about 416,035 (333)

Naive versus memory CD4 T cell response to antigen. Memory cells are less dependent on accessory cell costimulation and can respond to many antigen-presenting cell types including resting B cells. [PDF]

, 1994
Michael Croft, Linda M. Bradley, Susan L. Swain   +2 more
openalex   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source

Interleukin-19 Abrogates Experimental Autoimmune Encephalomyelitis by Attenuating Antigen-Presenting Cell Activation. [PDF]

Front Immunol, 2021
Horiuchi H, Parajuli B, Komiya H, Ogawa Y, Jin S, Takahashi K, Azuma YT, Tanaka F, Suzumura A, Takeuchi H.   +9 more
europepmc   +1 more source

Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation

Molecular Oncology, EarlyView.
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza, Robert Carlsson, Coralie Gamper, Gayatri Chitale, Johan Bengzon, Gesine Paul   +5 more
wiley   +1 more source

Single cell transcriptomics correlate avian coronavirus prime vaccination efficacy with antigen-presenting cell preference. [PDF]

NPJ Vaccines
Li X, Liang Y, Zhang Y, Fa B, Liu Z, Cui L, Xi M, Feng S, Xu L, Liu X, Xiao Z, Liu S, Li H.   +12 more
europepmc   +1 more source

Myeloid antigen-presenting cell niches sustain antitumor T cells and license PD-1 blockade via CD28 costimulation. [PDF]

Cancer Cell, 2021
Duraiswamy J, Turrini R, Minasyan A, Barras D, Crespo I, Grimm AJ, Casado J, Genolet R, Benedetti F, Wicky A, Ioannidou K, Castro W, Neal C, Moriot A, Renaud-Tissot S, Anstett V, Fahr N, Tanyi JL, Eiva MA, Jacobson CA, Montone KT, Westergaard MCW, Svane IM, Kandalaft LE, Delorenzi M, Sorger PK, Färkkilä A, Michielin O, Zoete V, Carmona SJ, Foukas PG, Powell DJ, Rusakiewicz S, Doucey MA, Dangaj Laniti D, Coukos G.   +35 more
europepmc   +1 more source

Response of naive antigen-specific CD4+ T cells in vitro: characteristics and antigen-presenting cell requirements. [PDF]

, 1992
Michael Croft, David D. Duncan, Susan L. Swain   +2 more
openalex   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Identification of antigen-presenting cell-T cell interactions driving immune responses to food. [PDF]

Science
Campos Canesso MC, de Castro TBR, Nakandakari-Higa S, Lockhart A, Luehr J, Bortolatto J, Parsa R, Esterházy D, Lyu M, Liu TT, Murphy KM, Sonnenberg GF, Reis BS, Victora GD, Mucida D.   +14 more
europepmc   +1 more source

HLA-DQ-restricted CD4+ T cells specific to streptococcal antigen present in low but not in high responders. [PDF]

, 1991
Nobuhiro Kamikawaji, Kazuki Fujisawa, Hideyuki Yoshizumi, M Fukunaga, Michio Yasunami, Akinori Kimura, Y. Nishimura, T. Sasazuki   +7 more
openalex   +1 more source