Results 211 to 220 of about 416,035 (333)

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

SIRPα + CD209 + cell: a specialized antigen-presenting cell that contributes to anti-SIRPα/RT therapy in colorectal cancer. [PDF]

Cancer Immunol Immunother
Li Y, Lu W, Xia F, Deng Y, Jin X, Xuan Y, Wang Y, Shen L, Wan J, Zhang H, Li Y, Li X, Huang L, Zhang Z.   +13 more
europepmc   +1 more source

Improved safety of induced pluripotent stem cell-derived antigen-presenting cell-based cancer immunotherapy. [PDF]

Mol Ther Methods Clin Dev, 2021
Mashima H, Zhang R, Kobayashi T, Tsukamoto H, Liu T, Iwama T, Hagiya Y, Yamamoto M, Fukushima S, Okada S, Idiris A, Kaneko S, Nakatsura T, Ohdan H, Uemura Y.   +14 more
europepmc   +1 more source

Identification of a rabies virus T cell epitope on the basis of its similarity with a hepatitis B surface antigen peptide presented to T cells by the same MHC molecule (HLA-DPw4). [PDF]

, 1990
Esteban Celis, J K Larson, L. Ötvös, William H. Wunner   +3 more
openalex   +1 more source

Protein O‐glycosylation in the Bacteroidota phylum

FEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns, Dennis Svedberg, André Mateus   +2 more
wiley   +1 more source

Intratumoral antigen-presenting cell activation by a nanovesicle for the concurrent tertiary lymphoid structure de novo neogenesis. [PDF]

Sci Adv
Cheng R, Li S, Ma X, Zhuang W, Lei Y, He J, Liang C, Nie W, Xie HY.   +8 more
europepmc   +1 more source

STING negatively regulates allogeneic T-cell responses by constraining antigen-presenting cell function. [PDF]

Cell Mol Immunol, 2021
Wu Y, Tang CA, Mealer C, Bastian D, Hanief Sofi M, Tian L, Schutt S, Choi HJ, Ticer T, Zhang M, Sui X, Huang L, Mellor AL, Hu CA, Yu XZ.   +14 more
europepmc   +1 more source

Neuromodulin (GAP43): a neuronal protein kinase C substrate is also present in 0-2A glial cell lineage. Characterization of neuromodulin in secondary cultures of oligodendrocytes and comparison with the neuronal antigen. [PDF]

, 1990
Jean‐Christophe Deloulme, Thierry Janet, D C Au, Daniel R. Storm, M. Sensenbrenner, Jacques Baudier   +5 more
openalex   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source

Downregulation of the antigen presenting cell function(s) of pulmonary dendritic cells in vivo by resident alveolar macrophages. [PDF]

, 1993
Patrick G. Holt, J. Oliver, N. Bilyk, Christine McMenamin, Paul G. McMenamin, Georg Kraal, Theo Thepen   +6 more
openalex   +1 more source