Monoclonal IgG as antigens: reduction is an early intracellular event of their processing by antigen-presenting cells [PDF]
Lyse Santoro+5 more
openalex +1 more source
CD9‐association with PIP2 areas is regulated by a CD9 salt bridge
The tetraspanin CD9 has an intracellular salt bridge. If CD9 opens, open‐CD9 moves from PIP2‐rich areas to regions populated by its interaction partner EWI‐2. Hence, the state of the salt bridge regulates the distribution of CD9 and by this CD9‐EWI‐2 complex formation.
Yahya Homsi+2 more
wiley +1 more source
Enhanced tumor control activities of anti-mPD-L1 antibody and antigen-presenting cell-like natural killer cell in an allograft model. [PDF]
Hung YP+5 more
europepmc +1 more source
Tumor‐infiltrating dendritic cells are defective in their antigen‐presenting function and inducible B7 expression in rats [PDF]
Pascal Chaux+3 more
openalex +1 more source
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li+5 more
wiley +1 more source
Cloned dendritic cells can present exogenous antigens on both MHC class I and class II molecules. [PDF]
Zu T. Shen+3 more
openalex +1 more source
ABSTRACT Introduction The kappa‐free light chain (κ‐FLC) index is known to be highly sensitive and specific for diagnosing multiple sclerosis (MS), while little is understood about lambda (λ)‐FLC. This study assessed the κ‐FLC and λ‐FLC indices in autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy.
Michael Levraut+11 more
wiley +1 more source
Dendritic cells can present antigen in vivo in a tolerogenic or immunogenic fashion. [PDF]
Fred D. Finkelman+4 more
openalex +1 more source
Glial Fibrillary Acidic Protein Astrocytopathy Based on a Two‐Center Chinese Cohort Study
ABSTRACT Objective Glial fibrillary acidic protein astrocytopathy (GFAP‐A) is a recently defined nosological form belonging to the class of autoimmune inflammatory disorders affecting the central nervous system (CNS). Here, we report the clinical and MRI characteristics, treatment, and prognosis of a GFAP‐A cohort from two centers in China.
Ti Wu+13 more
wiley +1 more source
T cell infiltration on local CpG-B delivery in early-stage melanoma is predominantly related to CLEC9A+CD141+ cDC1 and CD14+ antigen-presenting cell recruitment. [PDF]
Koster BD+12 more
europepmc +1 more source