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Antigen Presenting Cells

1985
Three major issues were discussed in the workshop: (1) the role of antigen processing in T-cell activation and situations in which it may not be necessary for T-cell stimulation, (2) the differences in antigen presenting function of macrophages and dendritic cells and the ability of dendritic cells to process antigen, and (3) the role of the type of ...
Kozo Yokomuro, Jay A. Berzofsky
openaire   +2 more sources

Antigen-Presenting Cells in the Skin

Annual Review of Immunology, 2017
Professional antigen-presenting cells (APCs) in the skin include dendritic cells, monocytes, and macrophages. They are highly dynamic, with the capacity to enter skin from the peripheral circulation, patrol within tissue, and migrate through lymphatics to draining lymph nodes.
Daniel H. Kaplan   +3 more
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Antigen presentation to B cells

Current Opinion in Immunology, 1991
B lymphocytes encounter antigen within the body, which causes them to undergo clonal expansion, affinity maturation and differentiation to antibody-forming cells. How they come into contact with the immunogen, and the subsequent response induced is the subject of several recent reports.
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Are the Mast Cells Antigen Presenting Cells?

Immunological Investigations, 1989
Mast cells have an important role in allergic reactions secreting histamine and other mediators of immediate hypersensitivity. In the present study we evaluated major histocompatibility complex (MHC) class II antigen expression in mast cells and their possible role in antigen presentation.
J. Leone   +4 more
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Antigen‐presenting Cells for CD8+ T Cells

Immunological Reviews, 1990
Evidence is presented that a wide variety of cell types are capable of presenting class I alloantigens to purified unprimed CD8+ cells in the absence of added help. These cells include dendritic cells, a population of Ia- Thy 1- cells in spleen, peritoneal exudate cells and one of three T-tumor lines. Some cell types, e.g.
Jonathan Sprent, M Schaefer
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Antigen-presenting cells for unprimed T cells

Immunology Today, 1989
The triggering requirements of T cells differ for primed and unprimed cells: primed T cells can be triggered to produce lymphokines without viable antigen-presenting cells (APCs), apparently by crosslinking the T-cell receptor (TCR). Unprimed T cells do, however, require viable APCs and here Jonathan Sprent and Mary Schaefer review what type of cells ...
Jonathan Sprent, M Schaefer
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Corneal Antigen-Presenting Cells

2007
Corneal antigen-presenting cells (APCs) were thought to reside exclusively in the peripheral cornea. However, recent evidence demonstrates that the central cornea is also endowed with a heterogeneous population of bone marrow-derived cells, including epithelial Langerhans cells (LCs) and anterior stromal dendritic cells (DCs), which under certain ...
Pedram Hamrah, Reza Dana
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Epithelial cell antigen presentation

Current Opinion in Gastroenterology, 2000
For decades intestinal epithelial cells were thought of as passive barriers to luminal contents, cells involved in nutrient absorption and electrolyte secretion. Studies during the past 10 to 15 years have changed that concept as our understanding of mucosal immunity has evolved and as we have come to understand that the regulation of this system is ...
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Antigen-Presenting Cells in the Decidua

2005
Maternal tolerance against fetal antigens is still one of the unsolved questions in pregnancy. Focusing on the various subsets of immune cells playing in concert with the human immune system, tolerance induction is nowadays often accredited to a specialized group of immune cells, the antigen-presenting cells (APC).
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Antigen Presentation by Human Antigen‐Presenting Cells to Antigen‐Specific Xenogeneic Murine T Cells

Microbiology and Immunology, 1986
AbstractSuccessful antigen presentation by xenogeneic human antigen‐presenting cells (APC) to stimulate the proliferation of antigen‐specific, keyhole limpet hemocyanin (KLH)‐specific, ovelbumin (OVA)‐specific, and purified protein derivative of Mycobacterium tuberculosis (PPD)‐specific murine T cells was observed.
Akihiko Yano, Kouji Yabu
openaire   +3 more sources

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