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Single-cell observation of calcium signals in T cells and antigen-presenting cells during antigen presentation

Immunology Letters, 1995
Intracellular calcium ion mobilization in T-cell hybridomas and antigen-presenting cells (APC) during the interaction was observed using confocal fluorescence microscopy. No calcium signal was detected in non-activated T-cell hybridomas by antigen presentation.
Chikako Torigoe   +2 more
openaire   +2 more sources

B cells as antigen presenting cells

Cellular Immunology, 2005
Several characteristics confer on B cells the ability to present antigen efficiently: (1) they can find T cells in secondary lymphoid organs shortly after antigen entrance, (2) BCR-mediated endocytosis allows them to concentrate small amounts of specific antigen, and (3) BCR signaling and HLA-DO expression direct their antigen processing machinery to ...
openaire   +3 more sources

Antigen Presentation and T Cell Stimulation by Dendritic Cells

Annual Review of Immunology, 2002
Dendritic cells take up antigens in peripheral tissues, process them into proteolytic peptides, and load these peptides onto major histocompatibility complex (MHC) class I and II molecules. Dendritic cells then migrate to secondary lymphoid organs and become competent to present antigens to T lymphocytes, thus initiating antigen-specific immune ...
Guermonprez, P   +4 more
openaire   +3 more sources

Artificial Antigen-Presenting Cells for Immunotherapies

2017
Artificial antigen-presenting cells (aAPCs) overcome many of the limitations of biologically based adoptive immunotherapy protocols. While these acellular systems can be designed with a variety of parameters, including material type, diameter, and proliferative signals for T cells, we outline methods to formulate and characterize a comprehensive ...
Dongin Kim   +3 more
openaire   +3 more sources

Antigen-presenting cells and T cell activation [PDF]

open access: possibleAgents and Actions, 1986
G. Huegli   +3 more
openaire   +2 more sources

Antigen-presenting cells and antigen presentation

2008
Louise J. Young, José A. Villadangos
openaire   +2 more sources

The Cell Biology of Antigen Presentation

Experimental Cell Research, 2002
Hidde L. Ploegh, Amy W. Hudson
openaire   +2 more sources

Antigen presenting cells and chimerism

Transplant Immunology, 1998
Lord, R, Vari, F, Goto, S, Sunagawa, M
openaire   +4 more sources

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