Results 331 to 340 of about 2,747,893 (386)

Antigen-presenting cell types

Current Opinion in Immunology, 1993
Different antigen-presenting cells elicit responses in different T-cell populations for primary activation, secondary stimulation and cytotoxic effector functions. Maturing bone marrow derived dendritic cells may acquire and process antigens, transport them to lymph nodes and activate naive T cells located there. By contrast, follicular dendritic cells,
S C, Knight, A J, Stagg
openaire   +2 more sources

Antigen presenting cells

Immunologic Research, 1989
A great deal has been learned over the past few years regarding the molecular biology of antigen presentation. These discoveries have been possible in part because of acquisition of protein sequencing data regarding class I and class II MHC molecules and in part because of X-ray crystallographic analysis of the three-dimensional structures of these ...
openaire   +2 more sources

Corneal Antigen-Presenting Cells

2007
Corneal antigen-presenting cells (APCs) were thought to reside exclusively in the peripheral cornea. However, recent evidence demonstrates that the central cornea is also endowed with a heterogeneous population of bone marrow-derived cells, including epithelial Langerhans cells (LCs) and anterior stromal dendritic cells (DCs), which under certain ...
Pedram, Hamrah, M Reza, Dana
openaire   +2 more sources

A class of γδ T cell receptors recognize the underside of the antigen-presenting molecule MR1

Science, 2019
A different way for γδ T cells to bind The ligands bound by γδ T cell receptors (TCRs) are less well characterized than those of their αβ TCR cousins, which are antigens presented by major histocompatibility complex (MHC) and related proteins.
J. L. Nours, J. L. Nours, N. Gherardin, N. Gherardin, Sri H. Ramarathinam, W. Awad, F. Wiede, F. Wiede, B. S. Gully, B. S. Gully, Y. Khandokar, T. Praveena, Jacinta Wubben, J. Sandow, J. Sandow, A. Webb, A. Webb, A. Borstel, A. Borstel, M. T. Rice, M. T. Rice, S. Redmond, Rebecca Seneviratna, Maria L. Sandoval-Romero, Shihan Li, Shihan Li, Michael N T Souter, S. Eckle, A. Corbett, H. Reid, H. Reid, Ligong Liu, D. Fairlie, E. Giles, G. Westall, G. Westall, R. Tothill, M. Davey, M. Davey, Richard Berry, Richard Berry, T. Tiganis, T. Tiganis, J. McCluskey, D. Pellicci, D. Pellicci, A. Purcell, Adam P. Uldrich, Adam P. Uldrich, D. Godfrey, D. Godfrey, J. Rossjohn, J. Rossjohn, J. Rossjohn   +53 more
semanticscholar   +1 more source

Epithelial cell antigen presentation

Current Opinion in Gastroenterology, 2000
For decades intestinal epithelial cells were thought of as passive barriers to luminal contents, cells involved in nutrient absorption and electrolyte secretion. Studies during the past 10 to 15 years have changed that concept as our understanding of mucosal immunity has evolved and as we have come to understand that the regulation of this system is ...
openaire   +2 more sources

Antigen presentation, antigen-presenting cells and antigen processing

Current Opinion in Immunology, 1988
To summarize, during the period under review there have been considerable advances in our understanding of how antigen is associated with MHC on the surface of a presenting cell. Basic rules which govern this association have been confirmed as including both the nature and the configuration of the antigen.
openaire   +2 more sources

T cells as antigen-presenting cells

Immunology Today, 1994
Human T cells express major histocompatibility complex (MHC) class II antigens and adhesion molecules characteristic of antigen-presenting cells (APCs), and recent in vitro and in vivo evidence supports an antigen-presenting function for T cells. In this guise, T cells provide downregulatory signals for the immune response by inducing anergy in T cells
W J, Pichler, T, Wyss-Coray
openaire   +2 more sources

Antigen Presenting Cells

1985
Three major issues were discussed in the workshop: (1) the role of antigen processing in T-cell activation and situations in which it may not be necessary for T-cell stimulation, (2) the differences in antigen presenting function of macrophages and dendritic cells and the ability of dendritic cells to process antigen, and (3) the role of the type of ...
Jay A. Berzofsky, Kozo Yokomuro
openaire   +1 more source

Antigen Presentation to B Cells

Trends in Immunology, 2016
Unlike T cells that recognize digested peptides, B cells recognize their cognate antigen in its native form. The B cell receptor used in recognition can also be secreted to bind to antigens and initiate multiple effector functions such as phagocytosis, complement activation, or neutralization of receptors.
Balthasar A, Heesters, Cees E, van der Poel, Abhishek, Das, Michael C, Carroll   +3 more
openaire   +2 more sources

Cell biology of antigen presentation

Current Opinion in Immunology, 1993
MHC class I molecules present degradation products derived from intracellular proteins, whereas MHC class II molecules generally present peptides derived from extracellular or surface proteins. Recent insights into the cell biology of MHC class I and II molecules explain this difference.
J J, Neefjes, F, Momburg
openaire   +2 more sources