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Basophils as antigen presenting cells
Trends in Immunology, 2010Recent reports demonstrate that basophils act as antigen presenting cells to drive Th2 and IgE responses against protease and protein allergens and helminth parasites. Through MHC class II-dependent cognate interactions with CD4(+) T cells in the context of co-stimulatory molecules, and through secretion of IL-4, IL-13 and thymic stromal lymphopoietin,
Maddur, Mohan +2 more
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Antigen-presenting cells in allergy
Journal of Allergy and Clinical Immunology, 2001The complex interaction of the innate and adaptive immune system requires flexibility and cooperation among various cell types. In this regard, antigen-presenting-cells (APCs) play a pivotal role in transferring information from the periphery of the organism to lymphoid organs, where they initiate the activation of naive T cells.
D, von Bubnoff, E, Geiger, T, Bieber
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Activation and expansion of human T cells using artificial antigen-presenting cell scaffolds
Nature Protocols, 2020David K. Y. Zhang +2 more
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B cells as antigen presenting cells
Cellular Immunology, 2005Several characteristics confer on B cells the ability to present antigen efficiently: (1) they can find T cells in secondary lymphoid organs shortly after antigen entrance, (2) BCR-mediated endocytosis allows them to concentrate small amounts of specific antigen, and (3) BCR signaling and HLA-DO expression direct their antigen processing machinery to ...
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Antigen presentation to B cells
Current Opinion in Immunology, 1991B lymphocytes encounter antigen within the body, which causes them to undergo clonal expansion, affinity maturation and differentiation to antibody-forming cells. How they come into contact with the immunogen, and the subsequent response induced is the subject of several recent reports.
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Critical care management of chimeric antigen receptor T‐cell therapy recipients
Ca-A Cancer Journal for Clinicians, 2022Alexander Shimabukuro-Vornhagen +2 more
exaly
Antigen presenting cells and mechanisms of antigen presentation.
Critical reviews in immunology, 1985In this review we will examine the characteristics of the various cell types which have been shown to present antigens to helper and proliferating T cells and explore what is known about the requirements for antigen presentation by these cells. Cell types to be discussed include mononuclear phagocytes from a variety of tissues as well as nonphagocytic ...
R W, Chesnut, H M, Grey
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