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The dendritic cell side of the immunological synapse
Immune responses are initiated by the interactions between antigen-presenting cells (APCs), such as dendritic cells (DCs), with responder cells, such as T cells, via a tight cellular contact interface called the immunological synapse.
Verboogen Danielle R.J.+5 more
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Background At present, it is highly controversial whether pure mast cells can serve as antigen presenting cells, and it is not known whether the capacity of antigen presenting function is temporally restricted to a particular subset of differentiated ...
Sun Liangwu+6 more
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Targeting antigens to dendritic cell receptors for vaccine development [PDF]
Dendritic cells (DCs) are highly specialized antigen presenting cells of the immune system which play a key role in regulating immune responses. Depending on the method of antigen delivery, DCs stimulate immune responses or induce tolerance.
Apostolopoulos, Vasso+3 more
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Xinghan Liu,1 Yujun Xu,1 Lijie Yin,1 Yayi Hou,1,2 Shuli Zhao3 1The State Key Laboratory of Pharmaceutical Biotechnology, Division of Immunology, Medical School, Nanjing University, Nanjing, 210093, People’s Republic of China; 2Jiangsu Key Laboratory of ...
Liu X, Xu Y, Yin L, Hou Y, Zhao S
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In this study, we investigate the use of multifunctional smart radiotherapy biomaterials (SRBs) loaded with immunoadjuvants for boosting the abscopal effect of local radiotherapy (RT).
Michele Moreau+10 more
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Adaptive immune responses begin with cognate antigen presentation-dependent specific interaction between T cells and antigen-presenting cells. However, there have been limited reports on the isolation and analysis of these cellular complexes of T cell ...
Soichiro Kuwabara+6 more
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Telaah Sel Basofil Sebagai Sel Penyaji Antigen Pada Manusia
The discovery of basophils as antigen presenting cells in animals tries to raise a big question about the same role in humans. In order to solve the problem, the references had been searched through the US National Library of Medicine, National Institute
Safari Wahyu Jatmiko
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Immunonutrition before esophagectomy: Impact on immune surveillance mechanisms [PDF]
Preoperative oral immunonutrition was demonstrated to improve immune response and to decrease the infection rate in patients with cancer. This study aimed to assess how immunonutrition could influence the immune cell response in the mucosal ...
Agostini, Marco+12 more
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Rai14 is a novel interactor of Invariant chain that regulates macropinocytosis
Invariant chain (Ii, CD74) is a type II transmembrane glycoprotein that acts as a chaperone and facilitates the folding and transport of MHC II chains. By assisting the assembly and subcellular targeting of MHC II complexes, Ii has a wide impact on the ...
Natacha Lobos Patorniti+5 more
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We present and study an agent-based model of T-Cell cross-regulation in the adaptive immune system, which we apply to binary classification. Our method expands an existing analytical model of T-cell cross-regulation (Carneiro et al. in Immunol Rev 216(1):
Abi-Haidar, Alaa, Rocha, Luis M.
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