Results 241 to 250 of about 3,665,754 (387)
Specific Complement-Fixing Diagnostic Antigens for Viral and Rickettsial Diseases [PDF]
, 1948 Herald R. Cox
openalex +1 more source
Advanced Biology, EarlyView.This study optimized a cell‐based ELISA for HIT antibody detection using PF4‐coated breast cancer cells (MDA‐MB‐231). Enhanced binding was observed at 50 mM NaCl and 4% paraformaldehyde fixation. Live MDA‐MB‐231 and HCT‐116 cells demontrated superior sensitivity and specificity, providing a promising platelet‐free alternative for clinical HIT diagnosis.
Li‐Yu Chen +4 more
wiley +1 more source
Understanding antibody-target antigen interactions and the avidity effect using mathematical modelling. [PDF]
J R Soc InterfaceHeirene L +4 more
europepmc +1 more source
Advanced Biology, EarlyView.The glomerular filtration barrier (GFB) is the first step of blood filtration by the kidneys. The concerning increase of kidney diseases makes the development of new models essential. In this context, microphysiological glomerular filtration barriers focus on closely reproducing the physiological architecture of the in vivo GFB: podocytes, glomerular ...
Manon Miran +5 more
wiley +1 more source
<i>In silico</i> design of immunogenic antigen cocktail via affinity maturation-guided optimization. [PDF]
Bioinform AdvAbeer ANMN, Koo BS, Yoon BJ.
europepmc +1 more source
Advanced Biology, EarlyView.The novelty of this study showed that the injection of exosomes produced from ADMSCs in combination with Roflumilast poses a more favorable therapeutic outcome for CKD induced by Adriamycin, compared to therapy with exosomes or Roflumilast alone. Roflumilast and exosomes treatment lowered the expression of the apoptotic, fibrotic, and inflammatory ...
Mohamed Ali +5 more
wiley +1 more source
Artificial intelligence-driven computational methods for antibody design and optimization. [PDF]
MAbsVecchietti LF +7 more
europepmc +1 more source