Understanding the Enigmatic Dance of Immune-Mediated Viral Infections and Their Pathogenetic Mechanisms. [PDF]
Karabulut MC, Oğuzoğlu TÇ.
europepmc +1 more source
Plasma‐Treated Hydrogel for Combined RONS and Chemotherapy Delivery: A Proof‐of‐Concept In Ovo
This study explores plasma‐treated hydrogels (PTH) as a new way to deliver both reactive oxygen and nitrogen species and chemotherapy (Doxorubicin) directly to tumors. In ovo tests show effects after a single dose, especially in osteosarcoma tumors. Tumor weight decrease, and a resistance‐related protein is reduced.
Milica Živanić+9 more
wiley +1 more source
Sarcomatoid transformation of uterine myoma identified through physical examination: a case report. [PDF]
Zhou X, Wu C, Shi M.
europepmc +1 more source
Platinum‐Copper bimetallic nanoparticles may evolve depending on their synthesis under tumor microenvironment conditions and play a dual role as chemotherapeutic agents after releasing Cu ions and as near infrared photothermal agents with the Pt‐rich remaining frames.
Jose I. Garcia‐Peiro+7 more
wiley +1 more source
A novel mRNA-based multi-epitope vaccine for rabies virus computationally designed via reverse vaccinology and immunoinformatics. [PDF]
Tombari W+6 more
europepmc +1 more source
Magnetically Guided Mechanoactive Mineralization Scaffolds for Enhanced Bone Regeneration
A 3D‐printed ‘rebar‐concrete’ inspired scaffold (PGS‐P@MGel) synergizes spontaneous biomineralization with magneto‐mechanical stimulation through PDA@Fe3O4‐embedded hydrogel. This dual biointerface activates Piezo1/β‐catenin/YAP mechanotransduction axis, enhancing BMSCs osteogenesis and angiogenesis simultaneously.
Xuran Guo+10 more
wiley +1 more source
A Pharmacophore-Based Method for Rapid and Accurate Virtual Screening of Antibody Libraries against Antigens. [PDF]
Williams CI+4 more
europepmc +1 more source
Adalimumab‐Poloxamer Conjugate for Bio‐Better: Enhanced Stability and Function
Antibody‐polymer conjugates, particularly poloxamer conjugates, enhance antibody stability by improving tolerance to physicochemical stress and attenuating proteolysis by proteases. Furthermore, the higher affinity observed with poloxamer conjugation compared to standard PEGylation results in improved therapeutic efficacy in rheumatoid arthritis mouse ...
Jaewon Roh+3 more
wiley +1 more source
Towards Understanding the Basis of Brucella Antigen-Antibody Specificity. [PDF]
Sood A, Bundle DR, Woods RJ.
europepmc +1 more source