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Autoimmune Arthritis Induced by Immunization to Mycobacterial Antigens

2020
An autoimmune process is thought to underlie articular manifestations of diseases, i.e., rheumatic fever, rheumatoid arthritis, ankylosing spondylitis, Reiter’s syndrome, and other forms of reactive arthritis. The most direct evidence for the responsibility of mycobacteria in the etiology of autoimmune arthritis, however, stems from studies of adjuvant
Cohen, Irun R.   +4 more
openaire   +1 more source

Influence of light delivery on photodynamic synovectomy in an antigen-induced arthritis model for rheumatoid arthritis

Lasers in Surgery and Medicine, 1998
Minimally invasive synovectomy techniques have been unsuccessful due to lack of selectivity. The purpose of this study was to evaluate the potential of photodynamic therapy to destroy diseased synovium in an antigen-induced arthritis model.Three sets of experiments evaluated the biodistribution and treatment effects of Photofrin (PF) in rabbits with ...
K, Trauner   +6 more
openaire   +2 more sources

Photodynamic Synovectomy Using Benzoporphyrin Derivative in an Antigen‐induced Arthritis Model for Rheumatoid Arthritis

Photochemistry and Photobiology, 1998
ABSTRACTExperimental photodynamic therapy (PDT) has recently been adapted for the treatment of inflammatory and rheumatoid arthritis. The biodistribution of benzoporphyrin derivative monoacid ring A (BPD‐MA) and the effect of percutaneous light activation via intra‐articular bare cleaved optical fibers was investigated using a rabbit‐antigen‐induced ...
K B, Trauner   +5 more
openaire   +2 more sources

Tissue response to titanium implants in experimental antigen-induced arthritis

Biomaterials, 1993
The healing of threaded, non-alloyed titanium implants in bone was studied in an experimental model of monoarticular arthritis in New Zealand white rabbits. Immunization with bovine serum albumin (BSA) and repeated intra-articular injections with BSA elicited an immune response and clinical signs of inflammation.
L, Sennerby, P, Thomsen
openaire   +2 more sources

Antigen-Induced Arthritis in Rats Is Suppressed by the Inducing Antigen Administered Orally before, but Not after Immunization

Cellular Immunology, 1995
The effects of oral administration of methylated bovine serum albumin (mBSA) on antigen-induced arthritis (AIA) in rats that was induced by immunization with mBSA followed by the intraarticular injection of the same antigen were investigated. When mBSA was orally given to animals before immunization with the antigen, the development of AIA was markedly
openaire   +2 more sources

Mechanisms of thrombocytopenia in the acute phase of antigen-induced arthritis in rabbits

Prostaglandins, 1991
Arthritis induced in hyperimmune rabbits by the intra-articular injection of the specific antigen was associated with a fall in circulating platelet number that lasted up to 60 days. Pretreatment of the animals with indomethacin and econazol at doses that significantly decreased thromboxane levels in the synovial fluids reduced the arthritis-related ...
A J, Fernandes   +5 more
openaire   +2 more sources

The effects of sensitization protocols on arthritic responses in antigen-induced arthritis

Agents and Actions, 1989
Three different immunization protocols were studied for their effect on methylated bovine serum albumin (mBSA)-induced arthritis. Mice were immunized with mBSA in Freund's incomplete adjuvant containing dextran and challenged 3 weeks later with antigen in one knee. After 7-14 days a strong inflammatory reaction developed without significant erosions of
N D, Staite, L G, Cutshaw, C J, Dunn
openaire   +2 more sources

Exacerbation of antigen-induced arthritis after challenge with intravenous antigen.

Immunology, 1983
The occurrence and morphology of flare-up of arthritis after intravenous (i.v.) antigen administration was investigated in mice with on-going antigen-induced arthritis (AIA). Intravenous injection of 300 micrograms methylated bovine serum albumin (mBSA) in mice with unilateral arthritis induced by mBSA, elicited 6 weeks previously, caused clear flare ...
L B, van de Putte   +3 more
openaire   +1 more source

Antigen induced arthritis: antigen handling and chronicity of joint inflammation.

Agents and actions. Supplements, 1983
Data are summarized on antigen handling by the joint and the relevance of antigen retention for the chronicity of joint inflammation. Antigen retention may occur at collagenous structures of the joint, when antibodies are present in these tissues or simply when the charge of an antigen favours nonimmune binding at the highly charged collagenous tissues.
W B, van den Berg   +3 more
openaire   +1 more source

Pathogenesis of Antigen-Induced Arthritis

Clinical Orthopaedics and Related Research, 1973
M E, Steinberg   +3 more
openaire   +2 more sources

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