Results 251 to 260 of about 693,649 (301)
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Immunologic Research, 1989
A great deal has been learned over the past few years regarding the molecular biology of antigen presentation. These discoveries have been possible in part because of acquisition of protein sequencing data regarding class I and class II MHC molecules and in part because of X-ray crystallographic analysis of the three-dimensional structures of these ...
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A great deal has been learned over the past few years regarding the molecular biology of antigen presentation. These discoveries have been possible in part because of acquisition of protein sequencing data regarding class I and class II MHC molecules and in part because of X-ray crystallographic analysis of the three-dimensional structures of these ...
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Antigen presentation: Untapped peptides
Current Biology, 1993Abstract The transporters associated with antigen presentation, TAP1 and TAP2, can apparently by bypassed to allow TAP-independent presentation of peptides to T cells by MHC class i molecules.
M T, Heemels, H, Ploegh
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FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1989
This paper reviews some of the cellular events involved in the immune recognition of foreign proteins. The recognition of an antigen by T lymphocytes is essential for its effective elimination by the host. T lymphocytes of the CD4 or CD8 subset recognize antigen but only after the antigen is handled by antigen-handling cells (antigen-presenting cells).
E R, Unanue, J C, Cerottini
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This paper reviews some of the cellular events involved in the immune recognition of foreign proteins. The recognition of an antigen by T lymphocytes is essential for its effective elimination by the host. T lymphocytes of the CD4 or CD8 subset recognize antigen but only after the antigen is handled by antigen-handling cells (antigen-presenting cells).
E R, Unanue, J C, Cerottini
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Antigen Presentation – Recent Developments
International Archives of Allergy and Immunology, 1996Antigen presentation is principally a function of MHC molecules, assisted by a number of adhesion and co-stimulatory molecules not immediately involved in antigen handling. Each MHC molecule, class I or class II, presents peptides derived from self or foreign proteins according to individual rules which have been elucidated in detail for several dozens
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Mechanisms of Antigen Presentation
cclm, 1999AbstractT-lymphocytes recognize short peptide antigens bound stably to polymorphic major histocompatibility complex (MHC)-encoded glycoproteins expressed on the surface of antigen-presenting cells (APC). Two general pathways have evolved to generate peptide-MHC complexes.
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Antigen processing and presentation
Immunology Letters, 1990An overview of the various aspects of antigen degradation and presentation is given with special emphasis on the possible occurrence of variation in the enzymatic machinery present in different cells or individuals. Different procedures for epitope mapping are also presented as well as the characterization of universal epitopes in humans.
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Antigen presenting cells and mechanisms of antigen presentation.
Critical reviews in immunology, 1985In this review we will examine the characteristics of the various cell types which have been shown to present antigens to helper and proliferating T cells and explore what is known about the requirements for antigen presentation by these cells. Cell types to be discussed include mononuclear phagocytes from a variety of tissues as well as nonphagocytic ...
R W, Chesnut, H M, Grey
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