Results 331 to 340 of about 3,005,806 (377)

Soft Nanocarriers as Antimicrobial Co‐Delivery Systems to Combat Resistant Infections

Advanced Healthcare Materials, EarlyView.
Soft nanocarrier‐based co‐delivery systems present a versatile and promising platform for combating antimicrobial resistance (AMR) by enabling spatiotemporally controlled, pathogen‐specific drug release. Their tunable physicochemical properties allow for the co‐encapsulation of synergistic antimicrobial agents, optimization of drug ratios, and surface ...
Anamarija Nikoletic, Evangelos Natsaridis, Timon Flathmann, Daiane P. C. Quadros, Nubia Gogniat, Oya Tagit   +5 more
wiley   +1 more source

Association between transcriptomic metrics of exogenous antigen presentation and adaptive immunity with locoregional recurrence in localized estrogen receptor negative breast cancer: retrospective review of multi-institutional datasets. [PDF]

Breast Cancer Res
Robinson TJ, Liveringhouse CL, Wilson C, Friedman S, Nakashima J, Mills MN, Purcell JD, Figura NB, Dongliang D, Thapa R, Welsh E, Ahmed KA, Grass GD, Fridley BL, Diaz R.   +14 more
europepmc   +1 more source

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

Advanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq, Punnya Anil Kumar Jeeja, Sudip Kumar Dam, Sabya Sachi Das, Juan L. Vivero‐Escoto   +4 more
wiley   +1 more source

Varicella Zoster Virus Downregulates Expression of the Nonclassical Antigen Presentation Molecule CD1d. [PDF]

J Infect Dis
Traves R, Opadchy T, Slobedman B, Abendroth A.   +3 more
europepmc   +1 more source

An Animal‐Free Patient‐Derived Tissue‐Mimetic Biochip Model of the Human Synovial Membrane for Human‐Relevant Osteoarthritis Research

Advanced Healthcare Materials, EarlyView.
Reihs et al. present the development of a humanized, animal‐free synovial membrane model for osteoarthritis. Methods include 3D biochip cultures of human‐primary OA synoviocytes with matrix and serum surrogates. Results show replication of synovial architecture and increased Yap1 expression.
Eva I. Reihs, Alexander Stoegner, Mateo G. Vasconez Martínez, Markus M. Schreiner, Melanie Cezanne, Ruth Gruebl‐Barabas, Bettina Rodriguez‐Molina, Juergen Alphonsus, Silvia Hayer, Richard Lass, Iris Gerner, Florien Jenner, Wolfgang Holnthoner, Stefan Toegel, Peter Ertl, Hans P. Kiener, Reinhard Windhager, Mario Rothbauer   +17 more
wiley   +1 more source

Birinapant Reshapes the Tumor Immunopeptidome and Enhances Antigen Presentation. [PDF]

Int J Mol Sci
Zhang W, Sun S, Zhu W, Meng D, Hu W, Yang S, Gao M, Yao P, Wang Y, Wang Q, Ji J.   +10 more
europepmc   +1 more source

Elementary immunology [PDF]

, 2017
Gogolák, Péter, Koncz, Gábor
core  

Colon‐Targeted Natural Polysaccharide‐Berberine Armored Hydrogel for the Treatment of Colitis

Advanced Healthcare Materials, EarlyView.
In this research, a novel hydrogel system targeting the colon is developed, incorporating Rhubarb polysaccharides and berberine‐loaded dendrimer. This hydrogel, forms through intermolecular hydrogen bonding and electrostatic interactions, accumulates in colonic tissues, effectively alleviating pathological immune hyperactivation while modulating gut ...
Miao Guo, Bo Li, Hongyi Li, Yi Chen, Qin Yuan, Mingju Shui, Hefeng Zhou, Wei Hao, Shengpeng Wang   +8 more
wiley   +1 more source

Defective removal of invariant chain peptides from MHC class II suppresses tumor antigen presentation and promotes tumor growth. [PDF]

Cell Rep
Bandola-Simon J, Ito Y, Wucherpfennig KW, Roche PA.   +3 more
europepmc   +1 more source

Chaperone-mediated MHC-I peptide exchange in antigen presentation. [PDF]

IUCrJ
Jiang J, Natarajan K, Margulies DH.
europepmc   +1 more source