Results 351 to 360 of about 3,005,806 (377)
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Immunologic Research, 1989
A great deal has been learned over the past few years regarding the molecular biology of antigen presentation. These discoveries have been possible in part because of acquisition of protein sequencing data regarding class I and class II MHC molecules and in part because of X-ray crystallographic analysis of the three-dimensional structures of these ...
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A great deal has been learned over the past few years regarding the molecular biology of antigen presentation. These discoveries have been possible in part because of acquisition of protein sequencing data regarding class I and class II MHC molecules and in part because of X-ray crystallographic analysis of the three-dimensional structures of these ...
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Antigen Presentation by Liposomes
1985Abstract T cells respond to foreign antigen only when the latter is presented on the surface of an antigen-presenting cell (APC) together with a molecule encoded in the major histocompatibility complex (MHC). The nature of this antigen presentation is poorly understood. The difficulty of demonstrating soluble antigen serologically on the surface of APC,
Z. A. Nagy, Peter Walden, Jan Klein
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Mechanisms of Antigen Presentation
cclm, 1999AbstractT-lymphocytes recognize short peptide antigens bound stably to polymorphic major histocompatibility complex (MHC)-encoded glycoproteins expressed on the surface of antigen-presenting cells (APC). Two general pathways have evolved to generate peptide-MHC complexes.
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Antigen processing and presentation
2019Dendritic cells are at the center of immune responses. They are defined by their ability to sense the environment, take up and process antigen, migrate to secondary lymphoid organs, where they present antigens to the adaptive immune system. In particular, they present lipids and proteins from pathogens, which they encountered in peripheral tissues, to ...
Kotsias, Fiorella +2 more
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Antigen processing and presentation
Immunology Letters, 1990An overview of the various aspects of antigen degradation and presentation is given with special emphasis on the possible occurrence of variation in the enzymatic machinery present in different cells or individuals. Different procedures for epitope mapping are also presented as well as the characterization of universal epitopes in humans.
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Basophils as antigen presenting cells
Trends in Immunology, 2010Recent reports demonstrate that basophils act as antigen presenting cells to drive Th2 and IgE responses against protease and protein allergens and helminth parasites. Through MHC class II-dependent cognate interactions with CD4(+) T cells in the context of co-stimulatory molecules, and through secretion of IL-4, IL-13 and thymic stromal lymphopoietin,
Maddur, Mohan +2 more
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Antigen presentation in cancer — mechanisms and clinical implications for immunotherapy
Nature Reviews Clinical Oncology, 2023Kailin Yang, A. Halima, T. Chan
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Antigen presentation in cancer: insights into tumour immunogenicity and immune evasion
Nature Reviews. Cancer, 2021S. Jhunjhunwala, C. Hammer, L. Delamarre
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Antigen Presentation in the Lung
American Journal of Respiratory and Critical Care Medicine, 2000Studies from our laboratory and elsewhere have implicated populations of dendritic cells in lung and airway tissues as key regulators of both qualitative and quantitative aspects of T cell responses to local antigenic challenge. Under steady state conditions, they are specialized for uptake of antigen, and require additional maturation signals for full
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A guide to antigen processing and presentation
Nature reviews. Immunology, 2022Novalia Pishesha +2 more
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