Results 31 to 40 of about 13,481 (242)

Hemagglutinin-specific neutralization of subacute sclerosing panencephalitis viruses. [PDF]

open access: yesPLoS ONE, 2018
Subacute sclerosing panencephalitis (SSPE) is a progressive, lethal complication of measles caused by particular mutants of measles virus (MeV) that persist in the brain despite high levels of neutralizing antibodies.
Miguel Ángel Muñoz-Alía   +2 more
doaj   +1 more source

Growth Kinetics of Influenza C Virus Antigenic Mutants That Escaped from Anti-Hemagglutinin Esterase Monoclonal Antibodies and Viral Antigenic Changes Found in Field Isolates

open access: yesViruses, 2021
The antigenicity of the hemagglutinin esterase (HE) glycoprotein of influenza C virus is known to be stable; however, information about residues related to antigenic changes has not yet been fully acquired.
Yoko Matsuzaki   +6 more
doaj   +1 more source

The antigenic property of the H5N1 avian influenza viruses isolated in central China

open access: yesVirology Journal, 2012
Background Three influenza pandemics outbroke in the last century accompanied the viral antigen shift and drift, resulting in the change of antigenic property and the low cross protective ability of the existed antibody to the newly emerged pandemic ...
Zou Wei   +4 more
doaj   +1 more source

Resurgence and predominance of G3P[8] human rotaviruses in north-central Bangladesh, 2018–2019

open access: yesNew Microbes and New Infections, 2020
Predominance of genotype G3P[8] rotavirus was revealed for children and adults with diarrhoea in north-central Bangladesh for a 1-year period from September 2018.
R. Mazid   +10 more
doaj   +1 more source

Estimation of Reduction in Influenza Vaccine Effectiveness Due to Egg-Adaptation Changes—Systematic Literature Review and Expert Consensus

open access: yesVaccines, 2021
Background: Influenza vaccines are the main tool to prevent morbidity and mortality of the disease; however, egg adaptations associated with the choice of the manufacturing process may reduce their effectiveness.
Raul Ortiz de Lejarazu-Leonardo   +11 more
doaj   +1 more source

Sequence-based antigenic change prediction by a sparse learning method incorporating co-evolutionary information. [PDF]

open access: yesPLoS ONE, 2014
Rapid identification of influenza antigenic variants will be critical in selecting optimal vaccine candidates and thus a key to developing an effective vaccination program.
Jialiang Yang, Tong Zhang, Xiu-Feng Wan
doaj   +1 more source

Structural Consequences of Antigenic Variants of Human A/H3N2 Influenza Viruses

open access: yesViruses, 2023
The genetic basis of antigenic drift of human A/H3N2 influenza virus is crucial to understanding the constraints of influenza evolution and determinants of vaccine escape.
David Francis Burke
doaj   +1 more source

Focused antibody response to influenza linked to antigenic drift [PDF]

open access: yesJournal of Clinical Investigation, 2015
The selective pressure that drives antigenic changes in influenza viruses is thought to originate from the human immune response. Here, we have characterized the B cell repertoire from a previously vaccinated donor whose serum had reduced neutralizing activity against the recently evolved clade 6B H1N1pdm09 viruses.
Kuan-Ying A, Huang   +7 more
openaire   +2 more sources

Progressive antigenic drift and phylogeny of human influenza A(H3N2) virus over five consecutive seasons (2009–2013) in Hangzhou, China

open access: yesInternational Journal of Infectious Diseases, 2014
Vaccine efficacy (VE) can be affected by progressive antigenic drift or any new reassortment of influenza viruses. To effectively track the evolution of human influenza A(H3N2) virus circulating in Hangzhou, China, a total of 65 clinical specimens were ...
Tie-juan Shao   +5 more
doaj   +1 more source

An investigation of antigenic drift of neuraminidases of influenza A (H1N1) viruses [PDF]

open access: yesJournal of Hygiene, 1984
SUMMARYA newly developed lectin neuraminidase test (LNT) and a panel of mouse monoclonal and post-infection ferret antibodies have been used to analyse antigenic drift in N1 neuraminidases of influenza A viruses isolated between 1933 and 1957 and also between 1977 and 1980.
P, Luther, K C, Bergmann, J S, Oxford
openaire   +2 more sources

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