Results 11 to 20 of about 306,691 (236)
Assessing Antigenic Drift of Seasonal Influenza A(H3N2) and A(H1N1)pdm09 Viruses. [PDF]
PLoS ONE, 2015 Under selective pressure from the host immune system, antigenic epitopes of influenza virus hemagglutinin (HA) have continually evolved to escape antibody recognition, termed antigenic drift.
Nipaporn Tewawong +8 more
doaj +2 more sources
Patterns of predicted T-cell epitopes associated with antigenic drift in influenza H3N2 hemagglutinin. [PDF]
PLoS ONE, 2011 Antigenic drift allowing escape from neutralizing antibodies is an important feature of transmission and survival of influenza viruses in host populations.
E Jane Homan, Robert D Bremel
doaj +2 more sources
Changed epitopes drive the antigenic drift for influenza A (H3N2) viruses [PDF]
BMC Bioinformatics, 2011 Background In circulating influenza viruses, gradually accumulated mutations on the glycoprotein hemagglutinin (HA), which interacts with infectivity-neutralizing antibodies, lead to the escape of immune system (called antigenic drift).
Yang Jinn-Moon, Huang Jhang-Wei
doaj +2 more sources
Integrating influenza antigenic dynamics with molecular evolution [PDF]
eLife, 2014 Influenza viruses undergo continual antigenic evolution allowing mutant viruses to evade host immunity acquired to previous virus strains. Antigenic phenotype is often assessed through pairwise measurement of cross-reactivity between influenza strains ...
Trevor Bedford +9 more
doaj +2 more sources
International Journal of Infectious Diseases, 2014 Vaccine efficacy (VE) can be affected by progressive antigenic drift or any new reassortment of influenza viruses. To effectively track the evolution of human influenza A(H3N2) virus circulating in Hangzhou, China, a total of 65 clinical specimens were ...
Tie-juan Shao +5 more
doaj +2 more sources
Impact of antigenic and genetic drift on the serologic surveillance of H5N2 avian influenza viruses [PDF]
BMC Veterinary Research, 2010 Background Serologic surveillance of Avian Influenza (AI) viruses is carried out by the hemagglutination inhibition (HI) test using reference reagents.
Lucio Eduardo +5 more
doaj +2 more sources
The antigenic evolution of influenza: drift or thrift? [PDF]
, 2013 It is commonly assumed that antibody responses against the influenza virus are polarized in the following manner: strong antibody responses are directed at highly variable antigenic epitopes, which consequently undergo 'antigenic drift', while weak ...
Paul S. Wikramaratna (9971622) +3 more
core +6 more sources
Modeling Influenza Antigenic Shift and Drift with LEGO Bricks [PDF]
Journal of Microbiology & Biology Education, 2016 The concepts of antigenic shift and drift could be found in almost every microbiology and virology syllabus, usually taught in the context of Influenza virus biology.
Boriana Marintcheva
doaj +2 more sources
The role of genomics in tracking the evolution of influenza A virus. [PDF]
PLoS Pathogens, 2009 Influenza A virus causes annual epidemics and occasional pandemics of short-term respiratory infections associated with considerable morbidity and mortality.
Alice Carolyn McHardy, Ben Adams
doaj +1 more source
Modeling Infectious Bursal Disease Virus (IBDV) Antigenic Drift In Vitro. [PDF]
Viruses, 2022 Infectious bursal disease virus (IBDV) vaccines do not induce sterilizing immunity, and vaccinated birds can become infected with field strains. Vaccine-induced immune selection pressure drives the evolution of antigenic drift variants that accumulate ...
Asfor AS +5 more
europepmc +2 more sources