Results 121 to 130 of about 90,622 (257)

Affinity‐Tuned Albumin Hitchhiking Extends the Bioorthogonal Capture Window in Pretargeting Radiotheranostics

Advanced Healthcare Materials, EarlyView.
Pharmacokinetic engineering of clickable radioligands was achieved via albumin hitchhiking approach within a pretargeted radiotheranostics delivery platform. This approach reduced rapid renal elimination, expanded bioorthogonal capture window, boosted tumor uptake by ∼3.5‐fold, and improved the tumor‐to‐liver ratio by ∼6‐fold.
Xie He, Nicholas L. Fletcher, Gayathri R. Ediriweera, Yifei Zhu, James Humphries, Christopher B. Howard, Jiazheng Wang, Craig A. Bell, Kristian Kempe, Kristofer J. Thurecht   +9 more
wiley   +1 more source

Gellan Gum Fluid Gel System for Controlled‐Delivery of Cytokine‐Licensed MSC‐EVs to Enhance Corneal Repair in Limbal Stem Cell Deficiency

Advanced Healthcare Materials, EarlyView.
Gellan gum fluid gel (FG) enables controlled ocular delivery of mesenchymal stromal cell (MSC)‐derived extracellular vesicles (EV). Its shear‐thinning, solid‐liquid‐solid rheology ensures prolonged ocular retention. Sustained MSC‐EV release (∼18% in 6 hrs) supports effective EV ocular delivery.
Seyedmohammad Moosavizadeh, Ava Dashti, Thomas E. Robinson, Robyn Gaffey, Richard Moakes, Neil Lagali, Liam Grover, Thomas Ritter   +7 more
wiley   +1 more source

A Simple Method to Produce Recombinant Mammalian Serum Albumins in <i>Escherichia coli</i> Preserving Intact Antigenic Properties. [PDF]

Int J Mol Sci
Dolgova AS, Cherkashina AS, Shcherbakov AI, Lashkevich KA, Goptar IA, Lisyukova IP, Sudina AE, Stukolova OA.   +7 more
europepmc   +1 more source

Antigenic properties of hyaluronic acid [PDF]

Biochemical Journal, 1943
openaire   +2 more sources

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Receptor-binding specificity and antigenic properties of a genotype D1.1 A(H5N1) influenza virus isolated from a human. [PDF]

Emerg Microbes Infect
Kandeil A, Chopra P, Ray SD, Ghotekar BK, Ranadheera C, Jeevan T, Fabrizio T, Rubrum A, Boons GJ, Tompkins SM, Bastien N, Webby RJ.   +11 more
europepmc   +1 more source

Distinct antigenic properties of the SARS-CoV-2 Omicron lineages BA.4 and BA.5

, 2022
Willett BJ, Kurshan A, Thakur N, Newman J, Manali M, Tyson G, Logan N, Murcia PR, Snell LB, Edgeworth JD, Zhou J, Sukhova K, Amirthalingam G, Brown K, Charleston B, Malim MH, Thomson EC, Barclay WS, Bailey D, Doores KJ, Peacock TP.   +20 more
europepmc   +1 more source

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

Advanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi, Mario Palacios‐Corella, Arjan Mol, Salvador Pané, Josep Puigmartí‐Luis   +4 more
wiley   +1 more source

Chemical Inactivation of <i>Bacillus subtilis</i> Endospores Preserves Recombinant Protein Antigenic Properties. [PDF]

Microorganisms
Saperi AA, Hazan A, Zulkifli N, Lee HY, AbuBakar S.   +4 more
europepmc   +1 more source

Analysis of the Antigenic Properties of Membrane Proteins of Mycobacterium tuberculosis. [PDF]

Sci Rep, 2019
Li H, Liu L, Zhang WJ, Zhang X, Zheng J, Li L, Zhu X, Yang Q, Zhang M, Liu H, Chen X, Jin Q.   +11 more
europepmc   +1 more source