Results 131 to 140 of about 10,676,235 (336)

Expression and Antigenic Evaluation of VacA Antigenic Fragment of Helicobacter Pylori [PDF]

Iranian Journal of Basic Medical Sciences, 2013
Objective(s): Helicobacter pylori, a human specific gastric pathogen is a causative agent of chronic active gastritis. The vacuolating cytotoxin (VacA) is an effective virulence factor involved in gastric injury.
Leila Hasanzadeh, Ehsanollah Ghaznavi-Rad, Safieh Soufian, Vahideh Farjadi, Hamid Abtahi   +4 more
doaj  

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

Molecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor, Julio Celis, Ulrik Ringborg   +2 more
wiley   +1 more source

Identification and Characterization of Antigenic Properties of Schistosoma japonicum Heat Shock Protein 90α Derived Peptides. [PDF]

Pathogens, 2022
Shen C, Zhu X, Xu X, Chang H, Ni Y, Li C, He K, Chen L, Chen L, Hou M, Ji M, Xu Z.   +11 more
europepmc   +1 more source

IL-4 and IL-4 receptor expression is dispensable for the development and function of natural killer T cells.

PLoS ONE, 2013
CD4 T cells acquire functional properties including cytokine production upon antigenic stimulation through the T cell receptor (TCR) and differentiate into T helper (Th) cells. Th1 cells produce interferon (IFN)-γ and Th2 cells produce interleukin (IL)-4.
Archna Sharma, Rosa Berga-Bolanos, Dil Afroz Sultana, Jyoti Misra Sen   +3 more
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Checkpoint blockade and the stem‐like T cell trade‐off

Molecular Oncology, EarlyView.
Stem‐like T cells are key to the success of programmed cell death protein 1 (PD1) blockade, as they sustain long‐term anti‐tumor response by continuously generating effector CD8+ T cells. However, how these cells are maintained in cancer is not fully understood. Hor et al.
Julie M. Mazet, Johanna A. Joyce
wiley   +1 more source

Assessment of Immunogenic and Antigenic Properties of Recombinant Nucleocapsid Proteins of Five SARS-CoV-2 Variants in a Mouse Model. [PDF]

Viruses, 2023
Rak A, Gorbunov N, Kostevich V, Sokolov A, Prokopenko P, Rudenko L, Isakova-Sivak I.   +6 more
europepmc   +1 more source

The effect of tetrathionate on the stability and immunological properties of muscle triosephosphate dehydrogenases [PDF]

Tetrathionate effect on stability and immunological properties of muscle triosephosphate ...
Allison, W. S., Kaplan, N. O.
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Antigenic properties of the SARS-CoV-2 nucleoprotein are altered by the RNA admixture. [PDF]

PeerJ, 2022
Kolesov DE, Sinegubova MV, Safenkova IV, Vorobiev II, Orlova NA.   +4 more
europepmc   +1 more source