Results 31 to 40 of about 90,622 (257)

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke   +4 more
wiley   +1 more source

Serological characteristics of some putative hybrid individuals from a Pinus sylvestris x Pinus mugo hybrid swarm population

open access: yesActa Societatis Botanicorum Poloniae, 2014
The antigenic properties of some putative hybrid individuals from a hybrid swarm population were studied. All the plants were to a major or lesser degree intermediate between three pure taxa, i.e. P. sylvestris, P. mugo and P. uliginosa.
Wiesław Prus-Gowacki, Jerzy Szweykowski
doaj   +1 more source

Differentiation of Rhizoctonia spp. Based on their antigenic properties [PDF]

open access: yesJournal of Agricultural Sciences (Belgrade), 2002
Antigenic properties and serological relationship was investigated in binucleate and multinucleate Rhizoctonia spp. isolates from strawberries soybean, alfalfa and potato plants from Serbia, from Spain, anastomosis group testers and in strawberry roots ...
Vico Ivana M.   +2 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The Immunogenicity of Glutaraldehyde Inactivated PTx Is Determined by the Quantity of Neutralizing Epitopes

open access: yesVaccines
Background/Objectives: Chemically or genetically detoxified pertussis toxin (PTx) is a crucial antigen component of the acellular pertussis vaccine. Chemical detoxification using glutaraldehyde generally causes significant structural changes to the toxin.
Xi Wang   +5 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

The effect of the G141R egg-adaptive substitution on the biological properties of currently circulating B/Victoria-lineage influenza B viruses

open access: yesИнфекция и иммунитет
Despite the continuing interest in influenza infection and relevant pathogens, a significant number of publications in this field are devoted to influenza A viruses, while influenza B viruses receive less attention. In PubMed database, there are 10 times
Ekaterina A. Stepanova   +7 more
doaj   +1 more source

Using Sequence Data To Infer the Antigenicity of Influenza Virus

open access: yesmBio, 2013
The efficacy of current influenza vaccines requires a close antigenic match between circulating and vaccine strains. As such, timely identification of emerging influenza virus antigenic variants is central to the success of influenza vaccination programs.
Hailiang Sun   +7 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

ANTIGENIC PROPERTIES OF ARTIFICIAL POLYEPITOPE HIV IMMUNOGEN

open access: yesСибирский научный медицинский журнал, 2019
The development of immunogen being capable of providing protection against HIV-1 infection and progression is still topical and unsolved challenge.
A. P. Rudometov   +5 more
doaj   +1 more source

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