Results 21 to 30 of about 90,622 (257)

Structural and antigenic variation among diverse clade 2 H5N1 viruses. [PDF]

PLoS ONE, 2013
Antigenic variation among circulating H5N1 highly pathogenic avian influenza A viruses mandates the continuous production of strain-specific pre-pandemic vaccine candidates and represents a significant challenge for pandemic preparedness.
David A Shore, Hua Yang, Amanda L Balish, Samuel S Shepard, Paul J Carney, Jessie C Chang, Charles T Davis, Ruben O Donis, Julie M Villanueva, Alexander I Klimov, James Stevens   +10 more
doaj   +1 more source

Emergence of a new designated clade 16 with significant antigenic drift in hemagglutinin gene of H9N2 subtype avian influenza virus in eastern China

Emerging Microbes and Infections, 2023
H9N2 avian influenza viruses (AIVs) pose an increasing threat to the poultry industry worldwide and have pandemic potential. Vaccination has been principal prevention strategy to control H9N2 in China since 1998, but vaccine effectiveness is persistently
Xiyue Wang, Kaituo Liu, Yaqian Guo, Yuru Pei, Xia Chen, Xiaolong Lu, Ruyi Gao, Yu Chen, Min Gu, Jiao Hu, Xiaowen Liu, Shunlin Hu, Xin-an Jiao, Xiufan Liu, Xiaoquan Wang   +14 more
doaj   +1 more source

PROBLEMS OF ISOLATION, IDENTIFICATION AND ANTIGENIC CHARACTERIZATION OF RECENT HUMAN A(H3N2) INFLUENZA VIRUSES

Вопросы вирусологии, 2018
Human A (H3N2) influenza viruses are distinguished by a high rate of evolution and regularly cause epidemics around the world. Their ability to adapt and to escape from the host's immune response and to change their receptor specificity is very high ...
P. A. Petrova, N. I. Konovalova, D. M. Danilenko, A. D. Vasilieva, M. Yu. Eropkin   +4 more
doaj   +1 more source

DRIFT OF INFLUENA A(H3N2) VIRUS: BIOLOGICAL, ANTIGENIC AND GENETIC PROPERTIES IN EPIDEMIC SEASON 2016-2017 IN RUSSIA AND COUNTRIES OF THE NOTHERN HEMYSPHERE

Вопросы вирусологии, 2018
The article presents the features of the influenza virus circulation for the period from October 2016 to May 2017 in some territories of Russia collaborating with the D.I.
D. K. Lvov, E. I. Burtseva, E. S. Kirillova, L. V. Kolobukhina, E. A. Mukasheva, S. V. Trushakova, E. L. Feodoritova, L. N. Merkulova, K. G. Krasnoslobodtsev, E. O. Garina, I. T. Fedyakina, V. A. Aristova, R. V. Vartanyan, L. B. Kisteneva, P. G. Deryabin, A. G. Prilipov, A. G. Rosatkevich, N. V. Breslav, I. S. Kruzhkova, A. L. Belyaev, E. V. Aksel’Rod, G. K. Sadykova, O. V. Shlyapnikova, M. V. Bazarova, A. V. Devyatkin   +24 more
doaj   +1 more source

Plasticity of the Influenza Virus H5 HA Protein

mBio, 2021
The HA protein of influenza A viruses is the major viral antigen. In this study, we simultaneously introduced mutations at 17 amino acid positions of an H5 HA expected to affect antigenicity.
Huihui Kong, David F. Burke, Tiago Jose da Silva Lopes, Kosuke Takada, Masaki Imai, Gongxun Zhong, Masato Hatta, Shufang Fan, Shiho Chiba, Derek Smith, Gabriele Neumann, Yoshihiro Kawaoka   +11 more
doaj   +1 more source

Properties of Pandemic Influenza Virus Strains Isolated in the Territory of Russia

Проблемы особо опасных инфекций, 2009
The first cases of the disease caused by pandemic (H1N1) 2009 influenza virus in the territory of the Russian Federation were registered at the end of May, 2009. 3 strains of pandemic (H1N1)2009 influenza virus were isolated from patients.
G. G. Onischenko, A. P. Agafonov, O. K. Demina, A. A. Sergeev, V. A. Ternovoy, L. N. Shishkina, N. I. Bormotov, A. S. Kabanov, M. O. Skarnovich, A. N. Shikov, A. O. Sementsova, A. M. Shestopalov, S. N. Shpynov, E. A. Stavskiy, I. G. Drozdov   +14 more
doaj   +1 more source

Peculiarities of the influenza viruses circulation and their properties during 2018-2019 epidemic season in Russia and countries of the Northern Hemisphere

Проблемы особо опасных инфекций, 2019
Objective. To identify the drift variability of influenza viruses during the period of epidemic rise in the incidence of acute respiratory viral infections in the period 2018-2019.
D. K. Lvov, E. I. Burtseva, E. A. Mukasheva, L. V. Kolobukhina, V. S. Bogdanova, N. V. Bovin, E. L. Feodoritova, S. V. Trushakova, N. V. Breslav, I. M. Kirillov, L. N. Merkulova, I. T. Fedyakina, K. G. Krasnoslobodtsev, O. L. Voronina, E. I. Aksenova, M. S. Kunda, N. N. Ryzhova, S. V. Alkhovsky, R. V. Vartanyan, L. B. Kisteneva, A. G. Rosatkevich, I. S. Kruzhkova, M. V. Bazarova, S. V. Smetanina   +23 more
doaj   +1 more source

Hemagglutinin-specific neutralization of subacute sclerosing panencephalitis viruses. [PDF]

PLoS ONE, 2018
Subacute sclerosing panencephalitis (SSPE) is a progressive, lethal complication of measles caused by particular mutants of measles virus (MeV) that persist in the brain despite high levels of neutralizing antibodies.
Miguel Ángel Muñoz-Alía, Claude P Muller, Stephen J Russell   +2 more
doaj   +1 more source

Subtype- and antigenic site-specific differences in biophysical influences on evolution of influenza virus hemagglutinin

Virology Journal, 2012
Background Influenza virus undergoes rapid evolution by both antigenic shift and antigenic drift. Antibodies, particularly those binding near the receptor-binding site of hemagglutinin (HA) or the neuraminidase (NA) active site, are thought to be the ...
Stray Stephen J, Pittman Lindsey B
doaj   +1 more source

A COMPARATIVE CHARACTERISTIC OF ANTIGENIC PROPERTIES OF RECOMBINANT AND NATIVE HBS-ANTIGENS WITH G145R MUTATION AND EVALUATION OF THEIR IMMUNOGENICITY

Вопросы вирусологии, 2017
Background: One of the important reasons for spreading of hepatitis B virus (HBV) under conditions of vaccine pressure is emergence of escape mutations.
M. V. Konopleva, V. N. Borisova, M. V. Sokolova, A. A. Feldsherova, M. A. Krymskij, T. A. Semenenko, A. P. Suslov   +6 more
doaj   +1 more source