Results 161 to 170 of about 126,752 (271)

Olink Proteomics Analysis Reveals Heterogeneous Responses to FcRn Blockade in Anti‐AChR Antibody‐Positive Myasthenia Gravis: FGF‐19 as a Novel Biomarker

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to systematically observe the clinical manifestations, immune cell subsets, and dynamic changes in serological indicators in patients with myasthenia gravis (MG) before and after efgartigimod (EFG) treatment. Methods We analyzed the baseline data, laboratory parameters, and lymphocyte subset proportions in MG ...
Tiancheng Luo, Deyou Peng, Zhouao Zhang, Mingjin Yang, Xinyan Guo, Tianyu Ma, Xiaoyu Huang, Mingming Xu, Linlin Fu, Yong Zhang   +9 more
wiley   +1 more source

HA gene amino acid mutations contribute to antigenic variation and immune escape of H9N2 influenza virus. [PDF]

Vet Res, 2022
Zhu R, Xu S, Sun W, Li Q, Wang S, Shi H, Liu X.   +6 more
europepmc   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Continued antigenic variation of highly pathogenic avian influenza A (H7N9) virus in laying hens in China, 2020-2021. [PDF]

Virol Sin, 2022
Jiang W, Yin X, Liu S, Liang S, Peng C, Hou G, Li J, Yu X, Li Y, Wang J, Liu H.   +10 more
europepmc   +1 more source

Antigenic variation in malaria

Cell, 1995
Borst, Piet, Bitter, Wilbert, McCulloch, Richard, van Leeuwen, Fred, Rudenko, Gloria   +4 more
openaire   +3 more sources

Evaluation of the Efficacy and Safety of Satralizumab in a Pregnant NMOSD Patient With AQP4/MOG‐IgG Dual Seropositive: A Case Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Neuromyelitis Optica Spectrum Disorder (NMOSD) is a chronic autoimmune neuroinflammatory disease, typically characterized by antibodies against aquaporin 4 (AQP4‐IgG) or myelin oligodendrocyte glycoprotein (MOG‐IgG). Simultaneous seropositivity for both antibodies in a single patient is exceedingly rare.
Yeting Luo, Shuhua Xie, Xianghong Liu
wiley   +1 more source

The Plasmodium falciparum histone methyltransferase PfSET10 is dispensable for the regulation of antigenic variation and gene expression in blood-stage parasites. [PDF]

mSphere
Wyss M, Kanyal A, Niederwieser I, Bartfai R, Voss TS.   +4 more
europepmc   +2 more sources

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source

Identification of key residues involved in the neuraminidase antigenic variation of H9N2 influenza virus. [PDF]

Emerg Microbes Infect, 2021
Wang F, Wu J, Wang Y, Wan Z, Shao H, Qian K, Ye J, Qin A.   +7 more
europepmc   +1 more source

Structural analysis of antigenic variation and adaptive evolution of the H5N1 neuraminidase gene. [PDF]

PLoS Comput Biol
Adegbaju MS, Owo-Odusi O, Wirtz ET, Morenikeji OB, Ojurongbe O, Thomas BN.   +5 more
europepmc   +1 more source