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Flexible sweat sensor patch integrating graphene‑interfaced gold microelectrodes functionalized with bio‑receptors and ion‑selective membrane, coupled with a capillary‑driven microfluidic layer and portable potentiostat electronics for multiplexed monitoring of inflammatory, metabolic, and electrolyte biomarkers in microliter sweat volumes.
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Antigenic variation in Borrelia
Research in Microbiology, 1991Antigenic variation was demonstrated for the agent of relapsing fever, Borrelia hermsii. The phenomenon is correlated with changes in major surface proteins called Vmp. The genes encoding these antigens are located on linear plasmids. Expression occurs by transposition of genes encoding Vmp to a telomeric expression site located on another linear ...
I, Saint Girons, A G, Barbour
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Antigenic Variation in Trypanosomes
The American Journal of Tropical Medicine and Hygiene, 1977Abstract The several species of African trypanosomes pathogenic to man and domestic livestock may evade the immune response through a process of antigenic variation. This phenomenon is the major obstacle to immunization. Variation may be recognized in the form of sequential changes in the serological characteristics of the trypanosome
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Antigenic variation in trypanosomes
Nature, 1978In its mammalian host, Trypanosoma brucei is able to change the antigenic character of its glycoprotein surface coat and so evade the host's immune response. This phenotypic change seems to occur spontaneously in 1 in 10,000 individuals but is not due to genetic mutation: host antibody is not necessary for its induction but plays a selective part in ...
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Antigenic variation of trypanosomes
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 1985Etude de la biologie des trypanosomes et de la variation antigenique. Synthese des VSGS et structure de la paroi externe. Structure des telomeres, organisation chromosomique, specificite des genes telomeriques, activation non duplicative, conversion des telomeres transcription chez les trypanosomatides, controle des sites d'expression ...
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ANTIGENIC VARIATION IN AFRICAN TRYPANOSOMES
Annual Review of Microbiology, 1985Revue bibliographique des etudes sur la base moleculaire de la variation antigenique chez les trypanosomes, avec presentation d'un modele a 2 etapes pour l'activation d'un gene de VSG (glycoproteine de surface specifique de variant)
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Antigenic Variation in Giardia lamblia
Experimental Parasitology, 1989Giardia lamblia undergo surface antigenic variation in vitro and in vivo. The presence of variant trophozoites can be detected in clones after exposure to cytotoxic monoclonal antibodies. Surviving Giardia (progeny) no longer possess the initial major surface antigen which is replaced by new antigens.
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Antigenic Variation in Babesia
1977As babesiosis has been the subject of several recent reviews (Mahoney 1972; Riek 1968; Ristic 1970) and is the subject of another chapter in this volume (Callow, Chapter 8), I will only briefly present the evidence now available to show that antigenic variation also occurs in this disease.
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Antigenic variation in Trypanosoma equiperdum
Research in Microbiology, 1991Trypanosoma equiperdum is an African trypanosome that causes dourine in horses. Like the other African trypanosomes, T. equiperdum escapes elimination by the immune system of its host by using an elaborate system of antigenic variant. The trypanosomes are covered by a coat consisting of a single protein called the variable surface glycoprotein (VSG ...
C, Roth +5 more
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Antigenic Variation in Malaria
1977Like most protozoan infections malaria is usually chronic. Even in the absence of persistent exoerythrocytic infection parasites may remain in the blood for months after antiplasmodial antibody is detectable in the serum.
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