Results 91 to 100 of about 62,650 (255)
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Computational Evaluation of B Cell Epitope of 37 kDa Outer Membrane Protein H (OmpH) Pasteurella multocida Type B from Nusa Tenggara Timur (NTT), Indonesia [PDF]
The Iranian Journal of Veterinary Science and TechnologyHS is still a frequently reported endemic disease, with outbreaks in Indonesia. HS vaccines distributed in Indonesia exhibit various limitations. This study computationally evaluated the B-cell epitope of the 37-kDa OmpH derived from the amino acid ...
Firdausy Maulana, Didik Handijatno
doaj +1 more source
, 2016 A. Antigenicity profiles of MSP2 inferred from experimental immunisation of mice (black) and rabbits (red) are plotted against the sequence. Black bars (top) denote the location of epitopes of a panel of monoclonal antibodies to MSP2. B.
Vladimír Sklenář (2216614) +10 more
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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Antigenicity of Bovine Pericardium Determined by a Novel Immunoproteomic Approach
, 2017 Despite bovine pericardium (BP) being the primary biomaterial used in heart valve bioprostheses, recipient graft-specific immune responses remain a significant cause of graft failure.
Ailsa J. Dalgliesh +2 more
core +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Specific T cell induction using iron oxide based nanoparticles as subunit vaccine adjuvant
Human Vaccines & Immunotherapeutics, 2018 Metal-based nanoparticles (NPs) stimulate innate immunity; however, they have never been demonstrated to be capable of aiding the generation of specific cellular immune responses. Therefore, our objective was to evaluate whether iron oxide-based NPs have
Lázaro Moreira Marques Neto +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Antigenicity of Ehrlich Ascites Tumor Part 1, Antigenicity of Low Density Lipoprotein in Ehrlich Ascites Tumor [PDF]
, 1968 Antigenicity of insoluble lipoprotein (low density lipoprotein) in Ehrlich ascites tumor and its biochemical characters were studied. The cytotoxic effect of immunized male dd-mice serum globulin was examined by cell culture technique.
Tadatomo, Yasuo
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