Results 131 to 140 of about 320,891 (294)

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Mesenchymal Stem Cell‐Inspired Microneedle Platform for NIR‐responsive Immunomodulation and Accelerated Chronic Wound Healing

Advanced Materials, EarlyView.
The research demonstrates a Mesenchymal Stem Cell‐inspired microneedle platform (MSCi@MN) that addresses chronic diabetic wounds by combining MSC‐derived extracellular nanovesicles (NV)–DNA conjugates in microneedle tips with photothermal MXene in the patch layer.
Chan Ho Moon, Hee Gyeong Ko, Hyun Lee, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Jong Hwa Seo, Nayoung Lee, So Won Jeon, Yun‐A Kim, Jong Sang Yoon, Kyung‐Yup Cha, Min‐Ho Kang, Dong Yun Lee, Soo‐Hong Lee, Gi Doo Cha, Kisuk Yang, Donghyun Lim, Heemin Kang, Su Ryon Shin, Han Young Kim, Hyun‐Do Jung   +21 more
wiley   +1 more source

Antigen complex of opportunistic bacteria: Assessment of protective properties and toxicity in mice

Биопрепараты: Профилактика, диагностика, лечение
INTRODUCTION. Medicinal products based on various bacterial antigens effectively prevent diseases caused by opportunisitic bacteria. However, their large-scale use will require improved composition and production process.
A. V. Soldatenkova, N. G. Sidorov, S. A. Lazarev, A. P. Zherebtsov, N. A. Mikhailova   +4 more
doaj   +1 more source

Directed Functionalization of Recombinant Spider Silk Nonwoven Membranes with Antibodies Using Non‐Canonical Amino Acids

Advanced Materials, EarlyView.
A recombinant spider silk protein was functionalized by incorporating genetically encoded bio‐orthogonal reactive azido‐groups. The azido‐functionalized proteins were produced in a scalable biotechnological process, and particles, films, as well as nanofibers were established as anchorage for fully functional antibodies via site‐specific bio‐orthogonal
Claudia Lacombe, Charlotte Leonhardt, Martin Humenik, Birgit Wiltschi, Thomas Scheibel   +4 more
wiley   +1 more source

Intranasal delivery of mRNA expressing newly identified Acinetobacter baumannii antigens protects against bacterial lung disease

npj Vaccines
Vaccines are central to the strategy to control antimicrobial resistant (AMR) bacterial infections; one multidrug resistant pathogen of particular concern is Acinetobacter baumannii. In this study we identified two novel A.
Sophie L. Higham, Ziyin Wang, Valarmathy Murugaiah, Jihye Song, Chubicka Thomas, Houze Zhang, Uta Griesenbach, Eric W. F. W. Alton, Luke A. Granger, Andrea Flores Esparza, Beatriz Dias Barbieri, Paul G. Hitchen, Paul Kellam, Robin J. Shattock, Shiranee Sriskandan, Stephen T. Reece, John S. Tregoning   +16 more
doaj   +1 more source

The Vegan Villain Sets Out to The End of Summer: Functionalized Coatings as Biohybrid UV‐Sensors

Advanced Materials Interfaces, EarlyView.
This study introduces biohybrid coatings incorporating E. coli biomass expressing photoconvertible fluorescent proteins as UV‐A responsive elements. Upon irradiation at 400 nm, the coatings exhibit an irreversible fluorescence shift from green to red within 15 min. Notably, the photoconversion capability is retained after >1 year of storage.
Amelie Skopp, Matea Marosevic, Broder Rühmann, Volker Sieber   +3 more
wiley   +1 more source

Specific immunoassays confirm association of Mycobacterium avium subsp. paratuberculosis with type-1 but not type-2 diabetes mellitus [PDF]

, 2009
Background Mycobacterium avium subspecies paratuberculosis (MAP) is a versatile pathogen with a broad host range. Its association with type-1 diabetes mellitus (T1DM) has been recently proposed.
Ahmed, Niyaz, Fadda, Giovanni, Gerlach, Gerald, Hasnain, Seyed E., Paccagnini, Daniela, Rosu, Valentina, Sechi, Leonardo Antonio, Zanetti, Stefania Anna Lucia   +7 more
core  

Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao, Akmal Hidayat Bin Sabri, Mary B. McGuckin, Linlin Li, Zihao Wang, Eneko Larrañeta, Ryan F. Donnelly   +6 more
wiley   +1 more source

A protective role of gamma/delta T cells in primary infection with Listeria monocytogenes in mice. [PDF]

, 1992
We have previously reported that T cells bearing T cell receptors (TCRs) of gamma/delta type appear at a relatively early stage of primary infection with Listeria monocytogenes in mice.
Bluestone, JA, Hiromatsu, K, Matsumoto, K, Matsuzaki, G, Muramori, K, Nomoto, K, Ohga, S, Yoshikai, Y   +7 more
core  

Fabrication, Properties, and Applications of Scaffolds for Bone Tissue Regeneration

Advanced Materials Technologies, EarlyView.
This review explores cutting‐edge biomaterials and fabrication techniques for scaffolds in bone tissue regeneration. It conducts a critical comparison of various strategies, meticulously analyzes the key contradictions in the field, and outlines an integrated development path spanning from biomaterial selection to clinical application, while ...
Shangsi Chen, Min Wang
wiley   +1 more source