Results 171 to 180 of about 159,660 (245)

Research progress concerning the involvement of the intestinal microbiota in the occurrence and development of inflammatory bowel disease. [PDF]

World J Gastroenterol
Zheng L, Duan SL, Wang K.
europepmc   +1 more source

Differentiated T Lymphocytes and Cancer Cell Mitochondrial Metabolism to Enhance Radioimmunotherapy by a Biomimetic Nanozyme System

Advanced Science, EarlyView.
T cell membrane‐coated MgCO3/Fe‐CD nanozyme loaded with TEPP‐46 (TFMP) enhances breast cancer radioimmunotherapy by reprogramming mitochondrial metabolism in T cells and tumors. It targets PD‐L1, converts H2O2 into ROS, neutralizes acidity, and releases Mg2⁺/TEPP‐46 to boost T cell activation.
Hanyu Zhang, Yuhan Deng, Yantong Lu, Miao Wang, Kun Qiao, Zifan Yang, Shipeng Ning, Tong Liu   +7 more
wiley   +1 more source

Main genetic factors associated with inflammatory bowel diseases and their consequences on intestinal permeability: involvement in gut inflammation. [PDF]

J Gastroenterol
Mauduit A, Mas E, Solà-Tapias N, Ménard S, Barreau F.   +4 more
europepmc   +1 more source

Cancer Manipulates Adjacent Adipose Tissue to Exploit Fatty Acids via HIF‐1α/CCL2/PPARα Axis: A Metabolic Circuit to Support Tumor Progression

Advanced Science, EarlyView.
Cancer cells drive adjacent adipose tissue to release fatty acids by secreting CCL2, which activates PPARα‐dependent lipolysis. The resulting fatty acid influx amplifies HIF‐1α/CCL2 signaling, establishing a positive feedback loop that fuels tumor growth.
Jeong‐Eun Yun, Jieun Seo, Jiwon Koh, Seock‐Ah Im, Ki Yong Hong, Yeseon Son, Do‐Won Jeong, Junji Fukuda, Jong‐Wan Park, Yang‐Sook Chun   +9 more
wiley   +1 more source

IgG4 unveiled: navigating the interplay with Crohn's disease - from immunology insights to machine learning. [PDF]

Ann Med Surg (Lond)
Mohan A, Ghaffar U, Basharat A, Nawaz G, Khenhrani RR, Rimsha, Vera GJA, Lal PM, Tanush D, Khan MK, Duseja N, Sherazi SL, Vikash, Kumar V, Nanavaty D.   +14 more
europepmc   +1 more source

An Engineered Solidified Peptide Hemocyte Sponge as Nanomotor Storage to Combat Bacterial Colitis

Advanced Science, EarlyView.
Peptides immobilized via nickel coordination can stabilize the framework structure. Following coating with red blood cell membranes, these constructs are capable of continuously sequestering endotoxins and mitigating colonic pathogenic damage by alleviating bacterial‐induced ferroptosis.
Yuxin Fang, Jianming Yan, Tongxin Yu, Zichuan An, Kaikai Lv, Chenyu Xue, Hongyang Yu, Na Dong, Anshan Shan   +8 more
wiley   +1 more source

Diagnostic Performance of Chimeric Recombinant Antigens of Trypanosoma cruzi for Identifying Chagas Disease in Samples From Rio Grande do Sul. [PDF]

Trop Med Int Health
Silva ÂAO, de Leon ÍF, de Jesus FSS, Sampaio DD, Voigt ALB, Pinheiro NB, Bottari NB, Castaño-Barrios LM, Celedon PAF, Zanchin NIT, Marchini FK, Berne MEA, Santos FLN.   +12 more
europepmc   +1 more source

Elementary immunology [PDF]

, 2017
Gogolák, Péter, Koncz, Gábor
core  

Lactobacillus Salivarius‐Derived Indole‐3‐Acetic Acid Promotes AHR‐PARP1 Axis‐Mediated DNA Repair to Mitigate Intestinal Aging

Advanced Science, EarlyView.
Indole‐3‐acetic acid (IAA) acting as one of the aryl hydrocarbon receptor (AHR) endogenous ligands is identified to be derived from Lactobacillus salivarius via its catalytic enzyme (ALDH) rather than host cells. Lactobacillus salivarius and IAA supplementation effectively mitigate intestinal aging by facilitating AHR‐poly (ADP‐ribose) polymerase 1 ...
Zheng Cao, Cui Zhang, Hehua Lei, Weichuan Lin, Wenkai Yu, Xin Gao, Yanmeng He, Xinzhi Li, Qingwei Xiang, Zhiwen Zhang, Weifei Luo, Andrew D. Patterson, Limin Zhang, Gang Chen   +13 more
wiley   +1 more source

From pathogenic mechanisms to therapeutic perspectives: a review of gut microbiota and intestinal mucosal immunity in inflammatory bowel disease. [PDF]

Front Immunol
Han T, Zhang Y, Zheng G, Guo Y.
europepmc   +1 more source