Results 171 to 180 of about 830,599 (290)

On a Clear Day (CD)

open access: yes, 1993
Brian Torff is the bassist and responsible for two compositions (Brasil 79’, Blue Island Blues) on this CD. Recorded live at Concord Pavillion, Concord, CA, August 1980.https://digitalcommons.fairfield.edu/visualandperformingarts-music/1026/thumbnail ...
Torff, Brian Q., Shearing, George
core  

RBM25 Drives Hepatocellular Carcinoma Progression by Stabilizing YAP Through Regulating Oncogenic Splicing‐switch of MYPT1

open access: yesAdvanced Science, EarlyView.
This study establishes that the RBM25‐PRPF40A interaction modulates MYPT1 splicing, promoting the production of the oncogenic long isoform. This isoform stabilizes YAP by suppressing its phosphorylation and subsequent proteasomal degradation, ultimately accelerating tumor growth.
Wenjing Zhang   +14 more
wiley   +1 more source

Clonal overlap and convergent clustering of T cell receptor signatures in Crohn's disease in monozygotic twins. [PDF]

open access: yesInflamm Bowel Dis
Brand EC   +9 more
europepmc   +1 more source

Workin’ on a Bassline (CD)

open access: yes, 1997
Brian Torff composed, arranged and produced this CD in addition to playing the bass. He also contributed the vocals on \u27Workin\u27 on a bassline\u27.
Torff, Brian Q.   +2 more
core  

CHD8‐Dependent Chromatin Licensing Sustains Trophoblast Stem Cell Transcriptional Programs

open access: yesAdvanced Science, EarlyView.
In this study, Huang et al., identify chromatin remodeler CHD8 as an essential factor in TSC maintenance and placental development. CHD8‐dependent chromatin accessibility supports the occupancy of key trophoblast TFs and is coupled to KMT2A‐associated H3K4me3 deposition at TSC stem and cell cycle genes, providing a permissive chromatin environment for ...
Yuanyuan Huang   +16 more
wiley   +1 more source

Optimization of antibody binding by adjusting thermodynamic stability during the maturation of antibody affinities. [PDF]

open access: yesProtein Sci
Akazawa-Ogawa Y   +7 more
europepmc   +1 more source

The Deubiquitinase UCHL1 Drives Susceptibility to Atrial Fibrillation by Stabilizing CaMKII‐δ

open access: yesAdvanced Science, EarlyView.
UCHL1 is highly upregulated in mice and patients with AF. UCHL1 directly binds to and removes K48‐linked polyubiquitin chains from CaMKII‐δ at K251 and enhances CaMKII‐δ stability, which activates RyR2, disrupts Ca2+ handling, and promotes AF. These findings establish UCHL1 as a critical regulator of CaMKII‐δ stability and AF‐related Ca2+ handling ...
Hai‐Lian Bi   +6 more
wiley   +1 more source

Oral Recombinant Human Collagen III Protects Gastric Mucosa via G‐Quadruplex‐Mediated Activation of the Pla2g4a‐Prostaglandin Axis

open access: yesAdvanced Science, EarlyView.
Orally administered recombinant human type III collagen protects the gastric mucosa from ethanol‐induced injury by coordinating redox homeostasis, epithelial barrier repair, and arachidonic acid–prostaglandin metabolism. Gastric digestion releases the pentapeptide GPAEF, which interacts with the Pla2g4a promoter G‐quadruplex in a structure‐dependent ...
Xinyue Lan   +14 more
wiley   +1 more source

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