Results 221 to 230 of about 1,659,797 (312)

Stability convergence in natural antibodies with ultra-long hypervariable loops. [PDF]

open access: yesCommun Biol
Passon M   +6 more
europepmc   +1 more source

Pharmacology and safety of TAS5315, a Bruton tyrosine kinase inhibitor, in healthy volunteers: First‐in‐human, randomized, ascending‐dose studies

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim TAS5315 is a Bruton tyrosine kinase (Btk) inhibitor in development for autoimmune and allergic diseases, including rheumatoid arthritis (RA) and chronic spontaneous urticaria (CSU). Two clinical studies evaluated the pharmacology and safety of single and multiple oral doses of TAS5315.
Yuji Kumagai   +4 more
wiley   +1 more source

Elementary immunology [PDF]

open access: yes, 2017
Gogolák, Péter, Koncz, Gábor
core  

The mystique of organ transplantation [PDF]

open access: yes, 2005
Bach   +48 more
core   +1 more source

Pharmacogenomics in the UK National Health Service: Progress towards implementation

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Over the past decade there has been considerable and growing enthusiasm about the promise of using genomics to inform healthcare. In particular, using genetic data to inform prescribing practice has emerged as a compelling policy priority for health systems around the world, not least in the NHS.
John H. McDermott   +3 more
wiley   +1 more source

Engineering antibodies with cancer‐associated binding sites

open access: yesBMEMat, EarlyView.
This review describes antibodies that perform direct/indirect roles in cancer treatment by binding to effective targets and discusses how antibodies kill tumors and modulate tumor microenvironment through these targets. The classification of expression systems for antibody production is summarized to guide appropriate selection based on different ...
Yinqi Tian   +4 more
wiley   +1 more source

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