Chimeric antigen receptor T-cell therapy in systemic lupus erythematosus: From B cell depletion to immune reprogramming. [PDF]
Zhao W, Chen M, Long J, Lu P, Jin J.
europepmc +1 more source
Dual B -Cell Maturation Antigen/CD19 Chimeric Antigen Receptor- T Therapy for AL Amyloidosis : Targeting the Clone, Saving the Kidney. [PDF]
Sobczak K, Leick MB.
europepmc +1 more source
Analytical Performance of the Sysmex XF‐1600 Flow Cytometer in Routine Clinical Practice
ABSTRACT Introduction Flow cytometry systems are increasingly used for the identification and quantification of lymphocyte subpopulations, supporting the diagnosis and monitoring of hematological and immunological conditions. This study aimed to evaluate the analytical performance of the novel Sysmex XF‐1600 flow cytometer for lymphocyte subpopulation ...
Meritxell Deulofeu Figueras +6 more
wiley +1 more source
Mechanisms, optimization strategies, and salvage options for CAR-T cell therapy. [PDF]
Wu B +11 more
europepmc +1 more source
The Leukocyte Landscape Across Mouse Strains and Tissues
The blood, bone marrow, liver, lymph nodes, and spleen of naïve male mice contained unique immunobiomes which differed between commonly used strains. BALB‐derived strains exhibited helper‐ and innate‐biased immune profiles, C57BL/6J‐derived strains were enriched for cytotoxic and immune surveillance populations, and DBA/2 J mice displayed elevated γδ T
Ella Trolio +4 more
wiley +1 more source
B7 homolog 3-targeted CAR-T cells secreting EGFR T-cell engagers for improved control of glioblastoma progression. [PDF]
Zhang Z +9 more
europepmc +1 more source
Abstract Background Despite pre‐emptive treatment (PeT), cytomegalovirus (CMV) disease and reactivation remain a clinical concern. In Australia and New Zealand (ANZ), variability exists in the management of CMV for haematopoietic stem cell transplantation (HSCT) recipients.
Andrea Henden +13 more
wiley +1 more source
A multimodal viro-immunotherapy strategy for glioblastoma. [PDF]
Li J, Shi Y.
europepmc +1 more source
Abstract Chimeric antigen receptor (CAR) T‐cell therapies directed against cluster of differentiation 19 (CD19) are a standard of care for relapsed or refractory B‐cell lymphomas. Infection is the leading cause of non‐relapse mortality, and this risk may persist for years after CAR T‐cell receipt.
Aine Hurley +15 more
wiley +1 more source
Overcoming fratricide of CD86 targeting CAR-T cells by defined logic-gate CAR strategy. [PDF]
Riet T +7 more
europepmc +1 more source

