Results 231 to 240 of about 53,090 (292)
ABSTRACT CD19‐directed chimeric antigen receptor (CAR) T‐cell therapy has transformed outcomes for patients with relapsed or refractory (r/r) mantle cell lymphoma (MCL), yet more than 40% relapse within one year. Early identification of patients at risk for progression could inform post CAR‐T surveillance and consolidation strategies.
Snegha Ananth +12 more
wiley +1 more source
Stage-resolved mapping of RP105 (CD180)-negative B cells reveals residual plasmablast-lineage skewing in SLE: a cross-sectional study. [PDF]
Kanagawa A +6 more
europepmc +1 more source
Guardians of immunity: the role of tumour-draining lymph node in cancer immunity. [PDF]
Oo D, Sharma I, Xue J, Liao S.
europepmc +1 more source
ABSTRACT Pancytopenia accompanied by chimeric antigen receptor T cell (CAR‐T) therapy is termed immune effector cell‐associated hematopoietic toxicity (ICAHT), which is often sustained and refractory to supportive care. We report a case of a 52‐year‐old man with multiple myeloma who developed severe ICAHT with secondary myelofibrosis (sMF) after ...
Keishi Ogura +9 more
wiley +1 more source
CAR T cell engineering approaches to minimise toxicities. [PDF]
Hogben E, Schurich A, Graham C.
europepmc +1 more source
Bone Marrow Pathology in Cold Agglutinin‐Mediated Autoimmune Hemolytic Anemia: A Study of 56 Cases
ABSTRACT Cold agglutinin disease (CAD) is a rare form of autoimmune hemolytic anemia (AIHA). CAD occurs in the context of a small clonal B‐cell lymphoproliferation restricted to blood and/or bone marrow (BM), without overt or extramedullary lymphoma. The WHO‐HAEM5 introduced a description of the CAD‐associated lymphoproliferative disorder (CAD‐LPD) in ...
Anne‐Marie L. Becking +6 more
wiley +1 more source
We prepared five glycosylated liposomal nanoparticles (G‐LNPs) to investigate the role of glycosylation and protein corona in modulating the in vivo behavior of G‐LNPs. We show that IgG and complement C3 adsorption enhanced liposomal nanoparticle clearance, with IgG promoting subsequent C3 binding.
Yingjie Yu +18 more
wiley +2 more sources
Immune dysfunction and food-specific IgG associated erosive oral lichen planus: a two-hit pathogenic model. [PDF]
Yang Y, Yang L, Liu F, Cheng G, Fang Q.
europepmc +1 more source
High‐dimensional spectral cytometry of peripheral blood mononuclear cells at hospital admission revealed that acute pancreatitis patients who subsequently developed moderately‐to‐severe disease exhibited a specific reduction of circulating CD2 + CD8dim NKT‐like cells, which appear to acquire an altered cytotoxic‐like phenotype upon IL‐15 stimulation ...
Carolina González de Castro +10 more
wiley +1 more source
Adapting CAR-T and CAR-Treg cancer therapies for autoimmunity: innovations and challenges. [PDF]
Lovelace MD +3 more
europepmc +1 more source

