Results 231 to 240 of about 53,090 (292)

Post CAR‐T Measurable Residual Disease Monitoring in Mantle Cell Lymphoma Enables Early Detection of Disease Relapse

open access: yesAmerican Journal of Hematology, Volume 101, Issue 8, Page 1818-1827, August 2026.
ABSTRACT CD19‐directed chimeric antigen receptor (CAR) T‐cell therapy has transformed outcomes for patients with relapsed or refractory (r/r) mantle cell lymphoma (MCL), yet more than 40% relapse within one year. Early identification of patients at risk for progression could inform post CAR‐T surveillance and consolidation strategies.
Snegha Ananth   +12 more
wiley   +1 more source

Immune Effector Cell‐Associated Hematotoxicity With Secondary Myelofibrosis Following Idecabtagene‐Vicleucel for Multiple Myeloma, Comprehensively Treated With Autologous Hematopoietic Stem Cell Boosting

open access: yeseJHaem, Volume 7, Issue 4, August 2026.
ABSTRACT Pancytopenia accompanied by chimeric antigen receptor T cell (CAR‐T) therapy is termed immune effector cell‐associated hematopoietic toxicity (ICAHT), which is often sustained and refractory to supportive care. We report a case of a 52‐year‐old man with multiple myeloma who developed severe ICAHT with secondary myelofibrosis (sMF) after ...
Keishi Ogura   +9 more
wiley   +1 more source

CAR T cell engineering approaches to minimise toxicities. [PDF]

open access: yesExp Biol Med (Maywood)
Hogben E, Schurich A, Graham C.
europepmc   +1 more source

Bone Marrow Pathology in Cold Agglutinin‐Mediated Autoimmune Hemolytic Anemia: A Study of 56 Cases

open access: yesEuropean Journal of Haematology, Volume 117, Issue 2, Page 384-395, August 2026.
ABSTRACT Cold agglutinin disease (CAD) is a rare form of autoimmune hemolytic anemia (AIHA). CAD occurs in the context of a small clonal B‐cell lymphoproliferation restricted to blood and/or bone marrow (BM), without overt or extramedullary lymphoma. The WHO‐HAEM5 introduced a description of the CAD‐associated lymphoproliferative disorder (CAD‐LPD) in ...
Anne‐Marie L. Becking   +6 more
wiley   +1 more source

Incorporation of Novel Synthetic Glycolipids in Liposomal Nanoparticles Affects Opsonization and In Vivo Clearance

open access: yesAngewandte Chemie, Volume 138, Issue 28, 6 July 2026.
We prepared five glycosylated liposomal nanoparticles (G‐LNPs) to investigate the role of glycosylation and protein corona in modulating the in vivo behavior of G‐LNPs. We show that IgG and complement C3 adsorption enhanced liposomal nanoparticle clearance, with IgG promoting subsequent C3 binding.
Yingjie Yu   +18 more
wiley   +2 more sources

High‐Dimensional Immune Profiling Identifies Circulating NKT‐Like Cells Associated With Severity Outcome in Acute Pancreatitis at Disease Onset

open access: yesImmunology, Volume 178, Issue 4, Page 685-703, August 2026.
High‐dimensional spectral cytometry of peripheral blood mononuclear cells at hospital admission revealed that acute pancreatitis patients who subsequently developed moderately‐to‐severe disease exhibited a specific reduction of circulating CD2 + CD8dim NKT‐like cells, which appear to acquire an altered cytotoxic‐like phenotype upon IL‐15 stimulation ...
Carolina González de Castro   +10 more
wiley   +1 more source

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